CAS No.121-24-4,GSSG Suppliers

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Basic Information

Molecular Structure:
CAS No.:	121-24-4
Name:	GSSG
Article Data:	168

Formula:	C20H32N6O12S2
Molecular Weight:	612.639
Synonyms:	L-GLUTATHIONE OXIDISED;L-GLUTATHIONE OXIDIZED;L-GLUTATHIONE (OXIDIZED FORM);CYCLIC(GAMMA-GLU-CYS-GLY);CYCLIC(GAMMA-GLU-CYS-GLY)2;GSSC;GSSG;(-)-GLUTATHIONE, OXIDIZED
EINECS:	248-170-7
Melting Point:	178 °C (dec.)(lit.)
Hazard Symbols:	Xi
Risk Codes:	R36/37/38
PSA:	368.24000
LogP:	-0.91260

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Chemistry

Chemical Name: GSSG
IUPAC NAME: 2-amino-5-[[3-[2-[(4-amino-5-hydroxy-5-oxopentanoyl)amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
CAS No.: 121-24-4
EINECS: 248-170-7
RTECS: MC0556500
Molecular Formula: C₂₀H₃₂N₆O₁₂S₂
Molecular Weight: 612.63 g/mol
Melting Point: 178 °C (dec.)(lit.)
Density: 1.54 g/cm³
Flash Point: 677.4 °C
Boiling Point: 1196.5 °C at 760 mmHg
Storage temp.: 2-8°C
Following is the structure of GSSG (CAS No.:121-24-4):

Product Categories about GSSG (CAS No.:121-24-4) is refer to Sulphur Derivatives
The chemical synonymous of GSSG (CAS No.:121-24-4) are L-Glutathione oxidised ; L-Glutathione (OXIDIZED FOrm) ; Cyclic(Gamma-Glu-Cys-Gly) ; Cyclic(Gamma-Glu-Cys-Gly)2 ; GSSC ; GSSG ; (-)-Glutathione, oxidized

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intravenous	> 2gm/kg (2000mg/kg)	Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
mouse	LD50	oral	> 5gm/kg (5000mg/kg)	Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
mouse	LD50	subcutaneous	> 2gm/kg (2000mg/kg)	Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
rat	LD50	intravenous	> 2gm/kg (2000mg/kg)	Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
rat	LD50	oral	> 5gm/kg (5000mg/kg)	Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.
rat	LD50	subcutaneous	> 2gm/kg (2000mg/kg)	Kiso to Rinsho. Clinical Report. Vol. 23, Pg. 6793, 1989.

Safety Profile

Hazard Codes: Irritant Xi
Risk Statements about GSSG (CAS No.:121-24-4):
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements about GSSG (CAS No.:121-24-4):
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.

Specification

GSSG (CAS No.:121-24-4) is a disulfide derived from two glutathione molecules.In living cells, glutathione disulfide is reduced into two molecules of glutathione with NADPH/H+ (Niacin Analog) catalyzed by the enzyme glutathione reductase. Antioxidant enzymes, such as glutathione peroxidases and glutaredoxins, generate glutathione disulfide during the reduction of hydroperoxides (RO-OH):
2GluSH + RO-OH → GluS-SGlu + ROH + H₂O