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1404-93-9

Basic Information
CAS No.: 1404-93-9
Name: Vancomycin hydrochloride
Molecular Structure:
Molecular Structure of 1404-93-9 (Vancomycin hydrochloride)
Formula: C66H75Cl2N9O24.HCl
Molecular Weight: 1485.73
Synonyms: Lyphocin;Meek;Vancocinehydrochloride;Vancocyn;Vancor;
EINECS: 215-772-6
Density: 1.657 g/cm3
Melting Point: >190°C (dec.)
Flash Point: 87℃
Solubility: 50 mg/mL in water,clear, yellow
Appearance: off white powder
Hazard Symbols: IrritantXi
Risk Codes: 43
Safety: 36/37-24/25-22-36
PSA: 530.49000
LogP: 4.73460
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  • low price CAS 1404-93-9 Vancomycin Hydrochloride hot selling

  • Casno:

    1404-93-9

    low price CAS 1404-93-9 Vancomycin Hydrochloride hot selling

    Min.Order: 1 Gram

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    Company Profile Shanghai CRM New Material Technology Co., Ltd , specializing in the production of research and development of pharmaceutical intermediates, this kind of products with high quality price concessions,

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  • Vancomycin hydrochloride CAS NO.1404-93-9 In stock

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    1404-93-9

    Vancomycin hydrochloride CAS NO.1404-93-9 In stock

    Min.Order: 25 Kilogram

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Chemistry

Product Name: Vancomycin hydrochloride
Molecular Structure of Vancocin hydrochloride (CAS NO.1404-93-9):

Molecular Formula: C66H75Cl2N9O24
Molecular Weight: 1449.2536
Synonyms of Vancocin hydrochloride (CAS NO.1404-93-9): Vancomycin hydrochloride [USAN] ; (3S-(3R*,6S*(S*),7S*,22S*,23R*,26R*,36S*,38aS*))-3-(2-Amino-2-oxoethyl)-44-((2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((4-methyl-2-(methylamino)-1-oxopentyl)amino)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid, monohydrochloride ; UNII-71WO621TJD ; Vancocin hydrochloride ; Vancocin hydrochloride in plastic container ; Vancocine hydrochloride ; Vancoled ; Vancomycin HCl ; Vancomycin monohydrochloride ; Vancor
CAS NO: 1404-93-9
Classification Code: Antibacterial ; Drug / Therapeutic Agent ; Human Data ; Reproductive Effect 
Index of Refraction: 1.734
Molar Refractivity: 350.83 cm3
Molar Volume: 874.6 cm3
Surface Tension: 105.1 dyne/cm
Density of Vancocin hydrochloride (CAS NO.1404-93-9): 1.65 g/cm3

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo intravenous 27500ug/kg/10 (27.5mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"
Clinical Pediatrics Vol. 23, Pg. 416, 1984.
guinea pig LD50 intraperitoneal 737mg/kg (737mg/kg) KIDNEY, URETER, AND BLADDER: HEMATURIA Antibiotics Annual. Vol. 4, Pg. 75, 1956/1957.
man LDLo intravenous 43mg/kg/2W-I (43mg/kg) BLOOD: AGRANULOCYTOSIS American Journal of Medicine. Vol. 81, Pg. 1059, 1986.
man TDLo intravenous 1429ug/kg/10- (1.429mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Mayo Clinic Proceedings. Vol. 61, Pg. 721, 1986.
mouse LD50 intraperitoneal 1734mg/kg (1734mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 933, 1981.
mouse LD50 intravenous 489mg/kg (489mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 933, 1981.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Antibiotics Annual. Vol. 4, Pg. 75, 1956/1957.
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg) BEHAVIORAL: GENERAL ANESTHETIC Antibiotics Annual. Vol. 4, Pg. 75, 1956/1957.
rat LD50 intraperitoneal 2218mg/kg (2218mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 933, 1981.
rat LD50 intravenous 319mg/kg (319mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 933, 1981.
rat LD50 oral > 10gm/kg (10000mg/kg)   Drugs in Japan Vol. 6, Pg. 597, 1982.
women TDLo intraperitoneal 40mg/kg (40mg/kg) GASTROINTESTINAL: PERITONITIS

BLOOD: CHANGES IN LEUCOCYTE (WBC) COUNT
American Journal of Kidney Diseases. Vol. 17, Pg. 76, 1991.
women TDLo intravenous 20mg/kg (20mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) Annals of Internal Medicine. Vol. 101, Pg. 880, 1984.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal routes. Human systemic effects by intravenous route: cardiac arrythmias, blood pressure lowering, and allergic dermatitis. When heated to decomposition it emits toxic fumes of NOx and HCl.
Hazard Codes of Vancocin hydrochloride (CAS NO.1404-93-9): IrritantXi
Risk Statements: 43 
R43: May cause sensitization by skin contact
Safety Statements: 36/37-24/25-22-36
S36/37: Wear suitable protective clothing and gloves
S24/25: Avoid contact with skin and eyes
S22: Do not breathe dust
S36: Wear suitable protective clothing
WGK Germany: 2
RTECS: YW4380000