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CAS No.: | 146-54-3 |
---|---|
Name: | triflupromazine |
Article Data: | 11 |
Molecular Structure: | |
Formula: | C18H19 F3 N2 S |
Molecular Weight: | 352.423 |
Synonyms: | Phenothiazine,10-[3-(dimethylamino)propyl]-2-(trifluoromethyl)- (6CI,8CI); 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine;2-(Trifluoromethyl)promazine; Fluopromazine; Psyquil; Siquil; Trifluopromazine;Triflupromazine |
Density: | 1.238g/cm3 |
Melting Point: | 25°C |
Boiling Point: | 427.6°Cat760mmHg |
Flash Point: | 212.4°C |
Solubility: | 1.762mg/L(24 oC) |
Safety: | Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES. |
PSA: | 31.78000 |
LogP: | 5.32480 |
Product Name: Triflupromazine (CAS NO.146-54-3)
Molecular Formula: C18H19F3N2S
Molecular Weight: 352.4170696g/mol
Mol File: 146-54-3.mol
Einecs: 205-673-6
Boiling point: 427.6 °C at 760 mmHg
Flash Point: 212.4 °C
Density: 1.238 g/cm3
Surface Tension: 39.1 dyne/cm
Enthalpy of Vaporization: 68.26 kJ/mol
Vapour Pressure: 1.62E-07 mmHg at 25°C
XLogP3-AA: 5.2
H-Bond Donor: 0
H-Bond Acceptor: 5
1. | dlt-mus-ipr 25 mg/kg | MUREAV Mutation Research. 17 (1973),87. | ||
2. | cyt-mam:kdy 10 mg/L/8H-C | FCTXAV Food and Cosmetics Toxicology. 8 (1970),617. | ||
3. | orl-rat LD50:185 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 36 (1986),797. | ||
4. | ipr-rat LD50:94 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 2 (1960),540. | ||
5. | orl-mus LD50:245 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 2 (1960),540. | ||
6. | ipr-mus LD50:100 mg/kg | MUREAV Mutation Research. 17 (1973),87. | ||
7. | ivn-mus LD50:44 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 2 (1960),540. |
EPA Genetic Toxicology Program.
Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES.
Triflupromazine ,its CAS NO. is 146-54-3,the synonyms is Dimethyl(3-(2-trifluoromethylphenothiazin-10-yl)propyl)amine ; Fluopromazine ; Triflupromazine ; Trifluoropromazine ; 10-[3-(Dimethylamino)propyl]-2-(trifluoromethyl)-10h-phenothiazine ; Trifluopromazine ; Vetame .