CAS No.16037-91-5,ANTIMONY SODIUM GLUCONATE Suppliers

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Basic Information

Molecular Structure:
CAS No.:	16037-91-5
Name:	ANTIMONY SODIUM GLUCONATE

Formula:	C12H20 O17 Sb2 . 9 H2 O . 3 Na
Molecular Weight:	1048.91
Synonyms:	D-Gluconicacid, 2,4:2',4'-O-(oxydistibylidyne)bis-, Sb,Sb'-dioxide, trisodium salt,nonahydrate;D-Gluconic acid, 2,4:2',4'-O-[oxybis(oxidostibylidyne)]bis-,trisodium salt, nonahydrate (9CI);Solustibosan (7CI);1,3,2-Dioxantimonane,D-gluconic acid deriv.;1,3,2-Dioxastibinane, D-gluconic acid deriv.;Antimony sodiumgluconate;D-Gluconic acid, cyclic ester with antimonic acid (H8Sb2O9) (2:1),trisodium salt, nonahydrate;Myostibin;Pentostam;Sodium stibogluconate;Solustin;Solusurmin;Solyusurmin;Stibanate;Stibanose;Stibatin;Stibinol;Stibogluconate sodium;
Density:	g/cm³
Boiling Point:	673.6°Cat760mmHg
Flash Point:	375.2°C
Hazard Symbols:	Xn,N
Risk Codes:	20/22-51/53
Safety:	Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of Sb.
PSA:	399.06000
LogP:	-8.81310

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Chemistry

Product Name: Antimony sodium gluconate
Synonyms: Antimony sodium gluconate
Molecular Structure of Antimony sodium gluconate (CAS NO.16037-91-5) :
Molecular Formula of Antimony sodium gluconate (CAS NO.16037-91-5) : C₁₂H₁₈Na₃O₁₇Sb₂
Molecular Weight of Antimony sodium gluconate (CAS NO.16037-91-5) : 746.75
CAS NO: 16037-91-5
Storage temp: 2-8°C
Solubility H₂O: 1 mg/mL at ~75 °C
Appearance: pale yellow solid
Appearance: white or slightly yellow amorphous powder significantly.
Solubility: soluble in hot water, soluble in water, insoluble in ethanol or ether. Odorless.

Uses

Antimony sodium gluconate (CAS NO.16037-91-5) is used as anti-leishmaniasis drugs.

Production

Calcium gluconate substitution reaction with sodium Carbonate to generate Sodium gluconate and then use the Antimony trichloride for Antimony trichloride reaction to get Trivalent sodium antimony gluconate, and finally Oxidation by hydrogen peroxide, obtaining Antimony sodium gluconate (CAS NO.16037-91-5) .

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	33mg/kg (33mg/kg)	Compilation of LD50 Values of New Drugs.
mouse	LD50	subcutaneous	7747mg/kg (7747mg/kg)	Indian Journal of Pharmacy. Vol. 11, Pg. 155, 1949.
mouse	LD50	unreported	1625mg/kg (1625mg/kg)	Drugs of the Future. Vol. 18, Pg. 451, 1993.

Consensus Reports

Antimony and its compounds are on the Community Right-To-Know List.

Safety Profile

Poison by intraperitoneal route. See also ANTIMONY COMPOUNDS. When heated to decomposition it emits toxic fumes of Sb.

RIDADR 3282
WGK Germany 3
RTECS CC7930000
HazardClass 6.1(b)
PackingGroup III

Standards and Recommendations

OSHA PEL: TWA 0.5 mg(Sb)/m³
ACGIH TLV: TWA 0.5 mg(Sb)/m³
NIOSH REL: TWA 0.5 mg(Sb)/m³