Products Categories
CAS No.: | 162118-01-6 |
---|---|
Name: | (S)-DIPHENYLALANINOL |
Article Data: | 4 |
Molecular Structure: | |
Formula: | C15H17 N O |
Molecular Weight: | 227.306 |
Synonyms: | Benzenepropanol,b-amino-g-phenyl-, (S)- (9CI) |
Density: | 1.113±0.06 g/cm3(Predicted) |
Boiling Point: | 410.0±40.0 °C(Predicted) |
PSA: | 46.25000 |
LogP: | 2.83840 |
tert-butyl N-[(1S)-1-(hydroxymethyl)-2,2-diphenylethyl]carbamate
(S)-2-amino-3,3-diphenyl-1-propanol
Conditions | Yield |
---|---|
With hydrogenchloride In tetrahydrofuran at 20℃; for 48h; Hydrolysis; | 100% |
With trifluoroacetic acid for 1h; Cooling with ice; |
(S)-2-amino-3,3-diphenyl-1-propanol
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran at 60℃; |
Conditions | Yield |
---|---|
With zinc(II) trifluoroacetate In chlorobenzene at 130℃; for 48h; Inert atmosphere; Schlenk technique; | 93% |
diethyl malonoimidate dihydrochloride
(S)-2-amino-3,3-diphenyl-1-propanol
Conditions | Yield |
---|---|
In dichloromethane at 40℃; for 8h; | 75% |
quinoline-2-carbonitrile
(S)-2-amino-3,3-diphenyl-1-propanol
Conditions | Yield |
---|---|
Stage #1: quinoline-2-carbonitrile With sodium methylate In methanol at 20℃; Stage #2: (S)-2-amino-3,3-diphenyl-1-propanol With toluene-4-sulfonic acid In toluene at 80℃; | 64% |
ethyl 5-(benzyloxy)-6-((2-methoxyethyl)carbamoyl)-4-oxo-4H-pyran-3-carboxylate
(S)-2-amino-3,3-diphenyl-1-propanol
ethyl (S)-5-(benzyloxy)-1-(3-hydroxy-1,1-diphenylpropan-2-yl)-6-((2-methoxyethyl)carbamoyl)-4-oxo-1,4-dihydropyridine-3-carboxylate
Conditions | Yield |
---|---|
In 5,5-dimethyl-1,3-cyclohexadiene at 120℃; for 0.5h; | 52% |
With triethylamine In toluene at 90℃; for 1h; | 9.12 g |
pyridine-2,6-dinitrile
(S)-2-amino-3,3-diphenyl-1-propanol
Conditions | Yield |
---|---|
With zinc trifluoromethanesulfonate In toluene for 48h; Reflux; | 35% |
di-tert-butyl dicarbonate
(S)-2-amino-3,3-diphenyl-1-propanol
tert-butyl N-[(1S)-1-(hydroxymethyl)-2,2-diphenylethyl]carbamate
Conditions | Yield |
---|---|
In dichloromethane |
5-chlorothien-2-ylsulfonyl chloride
(S)-2-amino-3,3-diphenyl-1-propanol
C19H18ClNO3S2
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran |
diphenylamine-2,2'-dicarbonyl chloride
(S)-2-amino-3,3-diphenyl-1-propanol
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; |