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16882-23-8

Basic Information
CAS No.: 16882-23-8
Name: 4-METHOXY-3-METHYLPHENYLACETONE
Article Data: 4
Molecular Structure:
Molecular Structure of 16882-23-8 (4-METHOXY-3-METHYLPHENYLACETONE)
Formula: C11H14 O2
Molecular Weight: 178.231
Synonyms: 2-Propanone,1-(4-methoxy-m-tolyl)- (8CI); 1-(4-Methoxy-3-methylphenyl)-2-propanone
Density: 1.011±0.06 g/cm3(Predicted)
Boiling Point: 164-166 °C(Press: 10 Torr)
PSA: 26.30000
LogP: 2.13510
Synthetic route
714258-55-6

2-(4-methoxy-3-methyl-phenyl)-acetoacetonitrile

16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

Conditions
ConditionsYield
With sulfuric acid
117896-10-3

(4-methoxy-3-methylphenyl)magnesium bromide

78-95-5

chloroacetone

16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

Conditions
ConditionsYield
578-58-5

2-methylmethoxybenzene

16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aqueous formaldehyde; aqueous HCl; petroleum ether
3: ethanolic sodium ethylate
4: aqueous H2SO4
View Scheme
60736-71-2

3-methyl-4-methoxybenzyl chloride

16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
2: ethanolic sodium ethylate
3: aqueous H2SO4
View Scheme
75391-57-0

2-(4-methoxy-3-methylphenyl)acetonitrile

16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ethanolic sodium ethylate
2: aqueous H2SO4
View Scheme

1-(4-methoxy-3-methylphenyl)-2-nitroprop-1-ene

16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

Conditions
ConditionsYield
With acetic acid In methanol; dichloromethane; water
16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

114963-00-7

2-(4-methoxy-3-methyl-phenyl)-1-methyl-ethylamine

Conditions
ConditionsYield
With methanol; ammonia; nickel at 80 - 90℃; under 25742.8 Torr; Hydrogenation;
16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

74-89-5

methylamine

827611-22-3

[2-(4-methoxy-3-methyl-phenyl)-1-methyl-ethyl]-methyl-amine

Conditions
ConditionsYield
With methanol; nickel at 90 - 100℃; under 51485.6 Torr; Hydrogenation;
16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

4-(2-Amino-propyl)-2-methyl-phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Raney nickel; methanol; NH3 / 80 - 90 °C / 25742.8 Torr / Hydrogenation
2: aqueous HBr
View Scheme
16882-23-8

(4-methoxy-3-methyl-phenyl)-acetone

6036-83-5

2-Methyl-4-(2-methylamino-propyl)-phenol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Raney nickel; methanol / 90 - 100 °C / 51485.6 Torr / Hydrogenation
2: aqueous HBr
View Scheme
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