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17466-45-4

Basic Information
CAS No.: 17466-45-4
Name: Phalloidin
Article Data: 14
Molecular Structure:
Molecular Structure of 17466-45-4 (Phalloidin)
Formula: C35H48 N8 O11 S
Molecular Weight: 788.879
Synonyms: Cyclo[L-alanyl-D-threonyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-(4R)-4,5-dihydroxy-L-leucyl],cyclic (3?;6)-thioether;NSC 523214;Phalloidine;
EINECS: 241-484-5
Density: 1.51g/cm3
Melting Point: 280-282°
Boiling Point: 1370.5°Cat760mmHg
Flash Point: 782.6°C
Solubility: Toxicity data

Stability

    Stable. Incompatible with strong oxidizing agents.

Toxicology

    Very toxic. May be fatal if swallowed, inhaled orabsorbed through the skin.

    Toxicity data

Appearance: white powder
Hazard Symbols:
Risk Codes: 26/27/28
Safety: Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx, and NOx.
PSA: 316.92000
LogP: -1.83500
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Chemistry

Empirical Formula  of Phalloidine (CAS NO.17466-45-4): C35H48N8O11S
Molecular Weight: 788.8676 g/mol
Index of Refraction: 1.683
Density: 1.51 g/cm3
Flash Point: 782.6 °C
Enthalpy of Vaporization: 217.3 kJ/mol
Boiling Point: 1370.5 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25 °C
Structure of Phalloidine (CAS NO.17466-45-4):
            

Toxicity Data With Reference

1.    

mor-rat:lvr 1 µmol/L

    CYTZAM    Cytobiologie. 17 (1978),73.
2.    

dni-rat:lvr 100 nmol/L

    TOXIA6    Toxicon. 25 (1987),1265.
3.    

ipr-mus LD50:2 mg/kg

    NEJMAG    New England Journal of Medicine. 269 (1963),223.
4.    

ivn-mus LDLo:6600 µg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 190 (1938),406.
5.    

orl-mam LDLo:1000 µg/kg

    CTOXAO    Clinical Toxicology. 17 (1980),45.

Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition,  Phalloidine (CAS NO.17466-45-4) emits toxic fumes of SOx, and NOx.

Specification

 Phalloidine ,its cas register number is 17466-45-4. It also can be called Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl),cyclic (3,6)-sulfide and Phalloidine .