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19962-06-2

Basic Information
CAS No.: 19962-06-2
Name: N-BOC-3-AMINOPHENOL
Article Data: 49
Molecular Structure:
Molecular Structure of 19962-06-2 (N-BOC-3-AMINOPHENOL)
Formula: C11H15 N O3
Molecular Weight: 209.245
Synonyms: Carbamicacid, (3-hydroxyphenyl)-, 1,1-dimethylethyl ester (9CI); Carbanilic acid,m-hydroxy-, tert-butyl ester (8CI); 1,1-Dimethylethyl(3-hydroxyphenyl)carbamate; 3-(tert-Butoxycarbonylamino)phenol; NSC 222586;tert-Butyl 3-hydroxyphenylcarbamate
Density: 1.182g/cm3
Melting Point: 134-138 °C(lit.)
Boiling Point: 286.8°Cat760mmHg
Flash Point: 127.3°C
Hazard Symbols:
Risk Codes: 43
Safety:
Hazard Codes Xi
Risk Statements 43
Safety Statements 26-36/37
PSA: 58.56000
LogP: 2.81220
Synthetic route
24424-99-5

di-tert-butyl dicarbonate

591-27-5

m-Hydroxyaniline

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

Conditions
ConditionsYield
In tetrahydrofuran Reflux;100%
In tetrahydrofuran for 24h; Heating;96%
In tetrahydrofuran for 18h; Reflux;95%

tert-butyl (3-cyano-4,6-dimethylpyridin-2-yl) carbonate

591-27-5

m-Hydroxyaniline

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

Conditions
ConditionsYield
In ethanol for 1h; Reflux;94%
24424-99-5

di-tert-butyl dicarbonate

51642-25-2

3-azidophenol

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

Conditions
ConditionsYield
With hydrogen; Lindlar's catalyst In methanol at 20℃; under 760 Torr; for 6h;89%
1239374-10-7

tert-butyl 3-hydroxyphenyl(3-perfluorooctylpropoxy)carbamate

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

Conditions
ConditionsYield
With methanol; tris(propionitrile)tricarbonylmolybdenum(0) at 130℃; for 0.25h; Microwave irradiation; Inert atmosphere; chemoselective reaction;
19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

120381-42-2

4-fluoro-2-methylaminonitrobenzene

1123583-09-4

tert-butyl {3-[3-(methylamino)-4-nitrophenoxy]phenyl}carbamate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 14h;100%
19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

106-96-7

propargyl bromide

1333393-77-3

tert-butyl 3-(prop-2-ynyloxy)phenylcarbamate

Conditions
ConditionsYield
With potassium carbonate; sodium iodide In N,N-dimethyl-formamide at 68℃; for 45h;98%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 12h;80%
6226-25-1

2,2,2-trifluoroethyl trifluoromethanesulphonate

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

1357094-84-8

tert-butyl (3-(2,2,2-trifluoroethoxy)phenyl)carbamate

Conditions
ConditionsYield
With potassium carbonate In acetone at 50℃;97%
With potassium carbonate In acetone at 50℃; for 36h;97.3%
19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

2927-71-1

2,4-dichloro-5-fluoropyrimidine

1246610-46-7

C15H15ClFN3O3

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 110℃; for 16h;96%
6980-08-1

4-chloro-3-nitro-2-pyridinamine

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

956488-58-7

4-(3-N-(tert-butoxycarbonyl)aminophenoxy)-3-nitropyridin-2-amine

Conditions
ConditionsYield
Stage #1: tert-butyl 3-hydroxyphenylcarbamate With potassium tert-butylate In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
Stage #2: 4-chloro-3-nitro-2-pyridinamine In N,N-dimethyl-formamide at 80℃; for 20h; Inert atmosphere; Further stages;
96%
1196672-22-6

2-(bromomethyl)-6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridine

19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

1450659-44-5

tert-butyl (3-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methoxy)phenyl)-carbamate

Conditions
ConditionsYield
With potassium carbonate In acetone for 8h; Inert atmosphere; Reflux;90%
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