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22881-35-2

Basic Information
CAS No.: 22881-35-2
Name: FAMPROFAZONE
Article Data: 1
Molecular Structure:
Molecular Structure of 22881-35-2 (FAMPROFAZONE)
Formula: C24H31 N3 O
Molecular Weight: 377.53
Synonyms: 3-Pyrazolin-5-one,4-isopropyl-2-methyl-3-[[methyl(a-methylphenethyl)amino]methyl]-1-phenyl- (8CI); Famprofazone
Density: 1.083g/cm3
Melting Point: 132-133 °C(Solv: ethanol (64-17-5))
Boiling Point: 485.1°Cat760mmHg
Flash Point: 184.8°C
Hazard Symbols:
Risk Codes: 22
Safety:
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
WGK Germany 3
RTECS UQ9451000
PSA: 30.17000
LogP: 4.36240
Synthetic route
88913-09-1

Famprofazon N-oxide

A

300-57-2

allylbenzene

B

4075-96-1

1-phenyl-2-dimethylaminopropane

C

22881-35-2

Famprofazone

D

88913-10-4

3-(N-Hydroxy-N-methylaminomethyl)-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on

E

83957-93-1

3-Formyl-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on

F

83957-94-2

4-Isopropyl-2-methyl-3-(N-methyl-aminomethyl)-1-phenyl-3-pyrazolin-5-on

Conditions
ConditionsYield
In dichloromethane for 72h; Product distribution; Ambient temperature; various time, various solvent;
88913-09-1

Famprofazon N-oxide

A

4075-96-1

1-phenyl-2-dimethylaminopropane

B

22881-35-2

Famprofazone

C

83957-93-1

3-Formyl-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on

D

83957-94-2

4-Isopropyl-2-methyl-3-(N-methyl-aminomethyl)-1-phenyl-3-pyrazolin-5-on

E

88913-08-0

4-Isopropyl-2-methyl-3-

Conditions
ConditionsYield
With tartaric acid; ferric nitrate In water for 24h; Product distribution; Heating; also with 0.1 N HCl; various time;
22881-35-2

Famprofazone

A

7632-10-2

methamphetamin

B

83957-89-5

5-(hydroxymethyl)-4-isopropyl-1-methyl-2-phenyl-1H-pyrazol-3(2H)-one

C

2-Methyl-3-

D

83957-93-1

3-Formyl-4-isopropyl-2-methyl-1-phenyl-3-pyrazolin-5-on

E

83957-94-2

4-Isopropyl-2-methyl-3-(N-methyl-aminomethyl)-1-phenyl-3-pyrazolin-5-on

F

88913-08-0

4-Isopropyl-2-methyl-3-

Conditions
ConditionsYield
With hydrogenchloride for 100h; Product distribution; Heating;
22881-35-2

Famprofazone

91485-56-2

4-Isopropyl-1-methyl-5-{[methyl-(1-methyl-2-phenyl-ethyl)-amino]-methyl}-2-phenyl-1,2-dihydro-pyrazol-3-one; hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In diethyl ether
22881-35-2

Famprofazone

88913-09-1

Famprofazon N-oxide

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 5℃; for 0.166667h; Yield given;
Raw Materials
88913-09-1
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