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2477-73-8

Basic Information
CAS No.: 2477-73-8
Name: Hydromadinone
Molecular Structure:
Molecular Structure of 2477-73-8 (Hydromadinone)
Formula: C23H31 Cl O4
Molecular Weight: 406.95
Synonyms: Pregn-4-ene-3,20-dione,6a-chloro-17-hydroxy-, acetate(7CI,8CI); Progesterone, 6a-chloro-17-hydroxy-, acetate (6CI); 17-Acetoxy-6a-chloropregn-4-ene-3,20-dione; 6a-Chloro-17-acetoxyprogesterone; 6a-Chloro-17-hydroxyprogesteroneacetate; Hydromadinone acetate; NSC 33170
Density: 1.21g/cm3
Melting Point: 192 °C
Boiling Point: 519.3°Cat760mmHg
Flash Point: 174°C
PSA: 60.44000
LogP: 4.62650
Synthetic route
2658-74-4

17α-acetoxy-6β-chloropregn-4-ene-3,20-dione

2477-73-8

17α-acetoxy-6α-chloropregn-4-ene-3,20-dione

Conditions
ConditionsYield
With hydrogenchloride
16319-93-0

17-acetoxy-3-ethoxy-pregna-3,5-dien-20-one

2477-73-8

17α-acetoxy-6α-chloropregn-4-ene-3,20-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: HCl
View Scheme
2477-73-8

17α-acetoxy-6α-chloropregn-4-ene-3,20-dione

302-22-7

chlormadinone acetate

2477-73-8

17α-acetoxy-6α-chloropregn-4-ene-3,20-dione

151-69-9

17-acetoxy-6α-chloro-pregna-1,4-diene-3,20-dione

Conditions
ConditionsYield
With pyridine; selenium(IV) oxide; tert-butyl alcohol
With pyridine; selenium(IV) oxide; tert-butyl alcohol
2477-73-8

17α-acetoxy-6α-chloropregn-4-ene-3,20-dione

2143-39-7

6α-chloropregn-4-ene-3β,17α-diol-20-one 17-acetate

Conditions
ConditionsYield
With lithium tri(t-butoxy)aluminum hydride In tetrahydrofuran at 0℃;
2477-73-8

17α-acetoxy-6α-chloropregn-4-ene-3,20-dione

149-73-5

trimethyl orthoformate

27255-62-5

6-chloro-3-methoxy-17α-hydroxypregna-3,5-dien-20-one 17-acetate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In 1,4-dioxane
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