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CAS No.: | 2477-73-8 |
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Name: | Hydromadinone |
Molecular Structure: | |
Formula: | C23H31 Cl O4 |
Molecular Weight: | 406.95 |
Synonyms: | Pregn-4-ene-3,20-dione,6a-chloro-17-hydroxy-, acetate(7CI,8CI); Progesterone, 6a-chloro-17-hydroxy-, acetate (6CI); 17-Acetoxy-6a-chloropregn-4-ene-3,20-dione; 6a-Chloro-17-acetoxyprogesterone; 6a-Chloro-17-hydroxyprogesteroneacetate; Hydromadinone acetate; NSC 33170 |
Density: | 1.21g/cm3 |
Melting Point: | 192 °C |
Boiling Point: | 519.3°Cat760mmHg |
Flash Point: | 174°C |
PSA: | 60.44000 |
LogP: | 4.62650 |
17α-acetoxy-6β-chloropregn-4-ene-3,20-dione
17α-acetoxy-6α-chloropregn-4-ene-3,20-dione
Conditions | Yield |
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With hydrogenchloride |
17-acetoxy-3-ethoxy-pregna-3,5-dien-20-one
17α-acetoxy-6α-chloropregn-4-ene-3,20-dione
Conditions | Yield |
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Multi-step reaction with 2 steps 2: HCl View Scheme |
17α-acetoxy-6α-chloropregn-4-ene-3,20-dione
17-acetoxy-6α-chloro-pregna-1,4-diene-3,20-dione
Conditions | Yield |
---|---|
With pyridine; selenium(IV) oxide; tert-butyl alcohol | |
With pyridine; selenium(IV) oxide; tert-butyl alcohol |
17α-acetoxy-6α-chloropregn-4-ene-3,20-dione
6α-chloropregn-4-ene-3β,17α-diol-20-one 17-acetate
Conditions | Yield |
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With lithium tri(t-butoxy)aluminum hydride In tetrahydrofuran at 0℃; |
17α-acetoxy-6α-chloropregn-4-ene-3,20-dione
trimethyl orthoformate
6-chloro-3-methoxy-17α-hydroxypregna-3,5-dien-20-one 17-acetate
Conditions | Yield |
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With toluene-4-sulfonic acid In 1,4-dioxane |