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250694-07-6

Basic Information
CAS No.: 250694-07-6
Name: 3-(tetradecylcarbamoylamino)-4-trimethylammonio-butanoate
Article Data: 2
Molecular Structure:
Molecular Structure of 250694-07-6 (3-(tetradecylcarbamoylamino)-4-trimethylammonio-butanoate)
Formula: C22H45 N3 O3
Molecular Weight: 399.618
Synonyms: (R)-4-Trimethylammonio-3-[(tetradecylcarbamoyl)amino]butyrate;ST 1326;Teglicar;
Density: g/cm3
Boiling Point: °Cat760mmHg
Flash Point: °C
Appearance: white crystalline powder
PSA: 81.26000
LogP: 3.98330
Synthetic route
4877-14-9

tetradecyl isocyanate

98063-21-9

(R)-3-(amino)-4-(trimethylammonio)butanoate

250694-07-6

teglicar

Conditions
ConditionsYield
tetrabutyl-ammonium chloride In methanol at 5 - 20℃;90%
In dimethyl sulfoxide at 40℃; for 60h;57%
4897-84-1

Methyl 4-bromobutyrate

250694-07-6

teglicar

(R)-4-trimethylammonium-3-(tetradecylcarbamoylamino)-butyrate of 3-(methoxycarbonyl)-propyl bromide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50℃;87%
67-56-1

methanol

250694-07-6

teglicar

methyl (R)-4-trimethylammonium-3-(tetradecylcarbamoyl)-amino-butyrate chloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 40℃; for 72h;12%
250694-07-6

teglicar

(R)-4-trimethylammonium-3-(tetradecylcarbamoyl)amino-butyrate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water
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Specification

 Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach.For the detailed information of Teglicar, the solubility of Teglicar in water, the solubility of Teglicar in DMSO, the solubility of Teglicar in PBS buffer, the animal experiment (test) of Teglicar, the cell expriment (test) of Teglicar, the in vivo, in vitro and clinical trial test of Teglicar, the EC50, IC50,and Affinity of Teglicar, Please contact DC Chemicals.