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3506-09-0

Basic Information
CAS No.: 3506-09-0
Name: PROPRANOLOL HYDROCHLORIDE
Article Data: 7
Molecular Structure:
Molecular Structure of 3506-09-0 (PROPRANOLOL HYDROCHLORIDE)
Formula: C16H22ClNO2
Molecular Weight: 295.809
Synonyms: (RS)-1-[(1-METHYLETHYL)AMINO]-3-(1-NAPHTHALENYLOXY)-2-PROPANOL HYDROCHLORIDE;PROPRANOLOL HCL;(+/-)-PROPANOLOL HCL;PROPANOLOL HYDROCHLORIDE;1-(isopropylamino)-3-(1-naphthyloxy)-,hydrochloride,(+-)-2-propano;1-(ISOPROPYLAMINO)-3-(A-NAPHTHOXY)-2-PROPANOL HYDROCHLORIDE;(+)-1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL, HCL;(+/-)-1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL, HCL;(+/-)-1-ISOPROPYLAMINO-3-(1-NAPHTHYLOXY)-2-PROPANOL HYDROCHLORIDE;1-[ISOPROPYLAMINO]-3-[1-NAPHTHYLOXY]-2-PROPANOL HYDROCHLORIDE;DL-PROPRANOLOL HYDROCHLORIDE;AURORA KA-6762;dl-propranolol hcl;(±)-[2-hydroxy-3-(naphthyloxy)propyl]isopropylammonium chloride;DL-PROPRANOLOL HCL 99%;dl-propranololHClbp;dl-propranololhydrochloridebp;Propranolol Hydrochloride for pharmaceutical raw materials;PENTAPROPANOLOLHYDROCHLORIDE;(RS)-Propranolol hydrochloride;
EINECS: 206-268-7
Melting Point: 163-165 °C(lit.)
Boiling Point: 446.1oC at 760 mmHg
Flash Point: 223.6oC
Solubility: H2O: 50 mg/mL, clear, colorless
Appearance: white powder
Hazard Symbols: HarmfulXn
Risk Codes: 22
PSA: 41.49000
LogP: 3.77040
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Chemistry

IUPAC Name: 1-Naphthalen-1-yloxy-3-(propan-2-ylamino)propan-2-ol hydrochloride
The MF of Propranolol hydrochloride (CAS NO.3506-09-0) is C16H22ClNO2.

                          
The MW of Propranolol hydrochloride (CAS NO.3506-09-0) is 295.8.
Synonyms of Propranolol hydrochloride (CAS NO.3506-09-0): 1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride ; Propranolol Hydrochloride ; (R,S)-Propranolol Hydrochloride ; 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol Hydrochloride
Solubility in H2O: 50 mg/mL, clear, colorless
Product Categories: Adrenoceptor
Flash Point: 216.8 °C 
Boiling Point: 434.9 °C
Melting Point: 163-165 °C
EINECS: 206-268-7
Storage temp: 2-8 °C 
Form: powder
Color: white

Uses

  Propranolol hydrochloride (CAS NO.3506-09-0) is used in chemical reagents, organic intermediates, fine chemicals, pharmaceutical research and development.

Toxicity Data With Reference

1.    

orl-mus LD50:380 mg/kg

    EJPHAZ    European Journal of Pharmacology. 15 (1971),151.
2.    

ipr-mus LD50:87,600 µg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 24 (1974),1751.
3.    

ivn-mus LD50:33,300 µg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 24 (1974),1751.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of HCl and NOx.Safety information of Propranolol hydrochloride (CAS NO.3506-09-0):
Hazard Codes  HarmfulXn
Risk Statements  
R22:Harmful if swallowed. 
RIDADR  3249
WGK Germany  3
RTECS  UB7525000
F  10
HazardClass  6.1(b)
PackingGroup  III