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CAS No.: | 35205-54-0 |
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Name: | 1-METHYL-2-PHENOXYETHYLAMINE |
Article Data: | 17 |
Molecular Structure: | |
Formula: | C9H13NO |
Molecular Weight: | 151.208 |
Synonyms: | 1-Phenoxypropan-2-amine; |
Density: | 1.004g/cm3 |
Melting Point: | 147-148 °C |
Boiling Point: | 240.5°Cat760mmHg |
Flash Point: | 99.5°C |
PSA: | 35.25000 |
LogP: | 2.11290 |
3-phenoxy-2-propanone
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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Stage #1: 3-phenoxy-2-propanone With ammonium formate In methanol at 80℃; for 0.166667h; Inert atmosphere; Stage #2: With formic acid; C29H32ClIrNO; triethylamine In methanol at 80℃; | 87% |
With 4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; ammonium formate In methanol at 80℃; for 12h; Inert atmosphere; chemoselective reaction; | 87% |
Stage #1: 3-phenoxy-2-propanone With ammonium formate In methanol at 80℃; for 0.166667h; Inert atmosphere; Stage #2: With formic acid; 4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; triethylamine In methanol at 80℃; Inert atmosphere; | 87% |
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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With hydrogen; nickel In isopropyl alcohol at 60℃; under 3102.9 Torr; 20-24 h; | 81% |
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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With hydrazine hydrate; acetic acid In methanol for 4h; Reflux; | 56% |
With hydrazine hydrate In ethanol |
1-phenoxy-2-propanol
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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Stage #1: 1-phenoxy-2-propanol In dichloromethane cooling; Stage #2: With dibenzyl azodicarboxylate In dichloromethane cooling; Stage #3: With trifluoroacetic acid In dichloromethane Further stages.; | 55% |
phenoxyacetone oxime
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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With nickel; benzene at 45℃; under 73550.8 Torr; Hydrogenation; | |
With diethyl ether; cyclohexane; nickel at 45℃; under 73550.8 Torr; Hydrogenation; | |
With lithium aluminium tetrahydride; diethyl ether | |
With lithium aluminium tetrahydride In diethyl ether for 12h; Heating; | |
With lithium aluminium tetrahydride In tetrahydrofuran for 3h; Reflux; |
3-phenoxy-2-propanone
formamide
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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Kochen des Reaktionsprodukts mit konz. wss. HCl; |
phenol
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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Multi-step reaction with 3 steps 1: sodium iodide; potassium carbonate / N,N-dimethyl-formamide 2: hydroxylamine hydrochloride; sodium hydroxide / 20 °C 3: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / Reflux View Scheme | |
Multi-step reaction with 2 steps 1.1: potassium carbonate / acetone / 0.5 h / 20 °C 1.2: 3 h / Reflux 2.1: formamide / water / 4 h / 185 °C View Scheme |
1-methyl-2-phenoxyethylamine
(2R,4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidin-2-one
Conditions | Yield |
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With triethylamine In tetrahydrofuran RT, 24 h, 65 deg C, 24 h; | 100% |
1-methyl-2-phenoxyethylamine
acetic anhydride
N-(1-methyl-2-phenoxyethyl)acetamide
Conditions | Yield |
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With triethylamine In tetrahydrofuran at 0℃; Inert atmosphere; | 93% |
1-methyl-2-phenoxyethylamine
Conditions | Yield |
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Stage #1: (2S)-4-methyl-2-isopropoxycarbonylaminopentanoic acid With isopropyl chloroformate; triethylamine In tetrahydrofuran at -3℃; for 1.5h; Stage #2: 1-methyl-2-phenoxyethylamine In tetrahydrofuran at 20℃; for 5.5h; | 83.2% |