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357336-20-0

Basic Information
CAS No.: 357336-20-0
Name: brivaracetam
Article Data: 50
Molecular Structure:
Molecular Structure of 357336-20-0 (brivaracetam)
Formula: C11H20 N2 O2
Molecular Weight: 212.292
Synonyms: Brivaracetam;UCB 34714
Density: 1.062
Melting Point: 76.38°
Boiling Point: 409.3±28.0 °C(Predicted)
PSA: 63.40000
LogP: 1.53710
Synthetic route
357338-13-7

(2S)-4,5-dehydro-(2-oxo-4-n-propyl-1-pyrrolidinyl)-2-butanamide

357336-20-0

brivaracetam

Conditions
ConditionsYield
With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; copper(l) chloride; sodium t-butanolate In toluene at -40℃; for 24h; Inert atmosphere;99.3%
With 5% Pd-CaCO3; hydrogen In methanol; water at -10 - 0℃; Temperature; Reagent/catalyst; Solvent;70.2%

(R)-N-((S)-1-amino-1-oxobutan-2-yl)-3-(chloromethyl)hexanamide

357336-20-0

brivaracetam

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran93%
With sodium hydroxide In dichloromethane at -15 - -10℃; Concentration; Reagent/catalyst; Temperature; Solvent;90%
With lithium hexamethyldisilazane In tetrahydrofuran at -15 - -5℃; for 4h;69.8%

ethyl (R)-γ-bromo-3-propylbutyrate

53726-14-0

(S)-2-amino-butanamide hydrochloride

357336-20-0

brivaracetam

Conditions
ConditionsYield
With sodium carbonate In ethanol at 50℃; for 24h; Temperature;93%

C7H13IO2

357336-20-0

brivaracetam

Conditions
ConditionsYield
Stage #1: C7H13IO2 With 1,1'-carbonyldiimidazole In toluene at 10 - 20℃; for 0.166667h; Inert atmosphere;
Stage #2: (S)-2-amino-butanamide In toluene at 10 - 20℃;
92%

ethyl (R)-γ-bromo-3-propylbutyrate

357336-20-0

brivaracetam

Conditions
ConditionsYield
With potassium carbonate In ethanol at 60℃; for 8h; Reagent/catalyst; Solvent; Temperature;91%
With tetra-(n-butyl)ammonium iodide; sodium carbonate In Isopropyl acetate at 88.8℃; for 28h; Inert atmosphere; Cooling;32%
Stage #1: (S)-2-amino-butanamide; ethyl (R)-γ-bromo-3-propylbutyrate With tetra-(n-butyl)ammonium iodide; sodium carbonate In Isopropyl acetate for 28h; Reflux;
Stage #2: With acetic acid In Isopropyl acetate at 60℃; for 1.83h;
12.66%

(2S)-2-[(4R)-2-oxo-4-n-propyl-1-pyrrolidinyl]butyric acid

357336-20-0

brivaracetam

Conditions
ConditionsYield
With ammonium chloride; N-ethyl-N,N-diisopropylamine; HATU In tetrahydrofuran at 20℃; for 2h; Time; Large scale;90%
With ammonia; pivaloyl chloride; triethylamine In dichloromethane at 0 - 10℃; for 6h; Inert atmosphere;88%
Stage #1: (2S)-2-[(4R)-2-oxo-4-n-propyl-1-pyrrolidinyl]butyric acid With chloroformic acid ethyl ester; triethylamine In dichloromethane at -10 - -5℃; for 1h;
Stage #2: With ammonium bicarbonate In dichloromethane at -10 - -5℃;
67%

C11H22N2O3*C2H2O4

357336-20-0

brivaracetam

Conditions
ConditionsYield
In isopropyl alcohol for 6h; Reflux;89.3%

isopropyl (2S)-2-[(4R)-2-oxo-4-propyl-1-pyrrolidinyl]butyrate

357336-20-0

brivaracetam

Conditions
ConditionsYield
With ammonium hydroxide; ammonia In water at 5℃; under 750.075 - 1125.11 Torr; for 15h;88.7%

C7H12ClIO

357336-20-0

brivaracetam

Conditions
ConditionsYield
With potassium hydroxide In dichloromethane at 0 - 5℃; for 2h; Molecular sieve;87%

methyl (2S)-2-[(4R)-2-oxo-4-propyl-1-pyrrolidinyl]butyrate

357336-20-0

brivaracetam

Conditions
ConditionsYield
With ammonium hydroxide In N,N-dimethyl-formamide at 20℃; for 15h;86.4%
With ammonium hydroxide; ammonia In water at 5℃; under 750.075 - 1125.11 Torr; for 15h;34 g
With ammonia In tetrahydrofuran at 20℃; for 20h;0.91 g
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    Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and qua

    Triumph International Development Limilted is engaged in the API, pharmaceutical intermediates research and developmen.Adhering to the "customer first" business philosophy,we suppl

  •  Triumph International Development Limilted

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-536-7971999

    Address:Yinhai Road,Shouguang

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  • UCB-34714 Brivaracetam 357336-20-0

  • Casno:

    357336-20-0

    UCB-34714 Brivaracetam 357336-20-0

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

    Taizhou Crene Biotechnology Co., Ltd.is a leading supplier of active pharmaceutical ingredients (APIs), with GLP labs and GMP manufacturing facilities engaging in organic synthesis

  •  Taizhou Crene Biotechnology co.ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-576-88813233 88205808

    Address:Economic Developed Zone of Taizhou Zhejiang China

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  • Factory Supply 99% Brivaracetam CAS 357336-20-0 with Best Price

  • Casno:

    357336-20-0

    Factory Supply 99% Brivaracetam CAS 357336-20-0 with Best Price

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-7.0

    Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other

    Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exp

  •  Hubei Yuanmeng Biological Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-027-68897569

    Address:Hongshan District

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  • BRIVARACETAM

  • Casno:

    357336-20-0

    BRIVARACETAM

    Min.Order: 1 Gram

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    Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

    AFINE CHEMICALS LIMITED is specialized in the fine chemicals and pharmaceuticals and we have enjoyed great popularity in world markets. Since 2005, we have been rapidly growing to

  •  Afine Chemicals Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-85134551

    Address:No. 206 Zhen Hua Road, Hangzhou 310030, Zhejiang, China

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  • brivaracetam CAS 357336-20-0

  • Casno:

    357336-20-0

    brivaracetam CAS 357336-20-0

    Min.Order: 1 Kilogram

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    brivaracetam CAS 357336-20-0 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2

    Hebei Miheng Trading Co.,Ltd is a professional manufacturer which integrate research and development, production and sales of chemical products in Hebei, China. Our company has bee

  •  Hebei Miheng Trading Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8615511060902

    Address:Handan city, Hebei province

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  • Brivaracetam

  • Casno:

    357336-20-0

    Brivaracetam

    Min.Order: 4 Kilogram

    FOB Price:  USD $ 0.0-0.0

    A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

    T&W GROUP was established in 2007, headquartered in Shanghai, China. By integrating people, technology and potential, we endeavor to work for a better life. We are in the business

  •  SHANGHAI T&W PHARMACEUTICAL CO., LTD.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-61551611

    Address:601, No. 1, 2277 Nong, Zu Chongzhi Road, Zhangjiang Hightech. Park, Pudong

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  • Brivaracetam

  • Casno:

    357336-20-0

    Brivaracetam

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

    Our company was funded in 2018. In order to adapt to the trend of world development, we established B2B e-commerce sector in Hangzhou. We supply raw material of chemicals, like API

  •  Hangzhou Fonlynn Health Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86 13291832373

    Address:Room 622, Building 11, Yifeng City, Nanyuan Street, Yuhang District

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  • Brivaracetam

  • Casno:

    357336-20-0

    Brivaracetam

    Min.Order: 10 Gram

    FOB Price:  USD $ 100.0-100.0

    Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

    Hangyu Biotech is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and O

  •  Zibo Hangyu Biotechnology Development Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-15965530500

    Address:Room1701, Tianxing Building,Licheng district, jinan, Shandong, China

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  • brivaracetam

  • Casno:

    357336-20-0

    brivaracetam

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0

    Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

    TaiChem was established in 2015 and registered in China medical city - Taizhou, Jiangsu Province. The company has about 1800 square meters of class A plant facility. TaiChem focuse

  •  TaiChem Taizhou Limited

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-0523-86810091

    Address:Changjiang Dadao 18

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  • brivaracetam

  • Casno:

    357336-20-0

    brivaracetam

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0

    Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

    Zibo Dorne chemical technology co., LTD. is a biotechnology enterprise engaged in the R&D, production and sales of drugs, steroids, peptides, raw materials, vitamins, food additive

  •  Zibo Dorne chemical technology co. LTD

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18560316533

    Address:No. 416, 4th floor, zhongguancun science and technology city, no. 1, west 6th road, zhangdian district

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  • Casno:

    357336-20-0

    brivaracetam

    Min.Order: 1 Milligram

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    GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

  •  Xiamen Jenny Chemical Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86

    Address:xiameng

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  • Brivaracetam

  • Casno:

    357336-20-0

    Brivaracetam

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 10.0-10.0

    Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api

    Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,an

  •  Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:0086-317-5106598

    Address:40# Shuiyuesi Street, Cangzhou City,Hebei Province, China.

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  • Supply and sell Pharmaceutical Raw Materials Brivaracetam for Anti-Epilepsy CAS 357336-20-0

  • Casno:

    357336-20-0

    Supply and sell Pharmaceutical Raw Materials Brivaracetam for Anti-Epilepsy CAS 357336-20-0

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 18.0-20.0

    factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

    Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in

  •  EAST CHEMSOURCES LIMITED

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15053231572

    Address:No.1581-12,Jinshui Road, Licang, Qingdao,China

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  • High Quality Brivaracetam

  • Casno:

    357336-20-0

    High Quality Brivaracetam

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0

    Product name: Brivaracetam CAS No.:357336-20-0 Molecule Formula:C11H20N2O2 Molecule Weight:212.29 Purity: 99.0% Package: 25kg/drum Description: White powder Manufacture Standards:Enterprise Standard TESTING ITEMS

    Siwei Development Group Ltd. is a reputed professional enterprise in China dedicated to the Amino Acids production and sales of fine chemical products.Over the years we have been m

  •  Siwei Development Group Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-571-82881840

    Address:Rm2-2-503 Zhongdingyuan, Xianghurenjia Wenyan Xiaoshan, Hangzhou China

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