CAS No.3652-90-2,2-BROMOCARBAZOLE Suppliers

Products Categories

Materials (139)
Pharmaceutical (139)
Organic Chemicals (59)
Others (24)
Reagent (5)
Agrochemicals (1)

Basic Information

Molecular Structure:
CAS No.:	3652-90-2
Name:	2-BROMOCARBAZOLE
Article Data:	64

Formula:	C₁₂H₈BrN
Molecular Weight:	246.106
Synonyms:	9H-Carbazole, 2-bromo-;2-Bromocarbazole;
EINECS:	807-979-0
Density:	1.617 g/cm³
Melting Point:	253.0 to 257.0 °C
Boiling Point:	409.228 °C at 760 mmHg
Flash Point:	201.294 °C
PSA:	15.79000
LogP:	4.08360

Synthetic route

: 2-bromo-9-(pyrimidin-2-yl)-9H-carbazole

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
With N1-(4-hydroxy-2,6-dimethylphenyl)-N2-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water; copper(l) chloride; sodium t-butanolate In dimethyl sulfoxide at 110℃; for 24h; Schlenk technique; Inert atmosphere;	99%

: 35450-34-1
4'-bromo-2-nitrobiphenyl

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
With triphenylphosphine In 1,2-dichloro-benzene at 170℃; for 12h; Inert atmosphere;	89%
With triethyl phosphite In 1,2-dichloro-benzene at 80 - 150℃; Inert atmosphere;	75%
Stage #1: 4'-bromo-2-nitrobiphenyl With triethyl phosphite at 160℃; for 2h; Stage #2: With hydrogenchloride In water for 1h; Reflux;	67.6%

2-bromo-9H-carbazole: 2-bromo-9H-carbazole

Conditions

Conditions	Yield
With potassium fluoride; tris-(dibenzylideneacetone)dipalladium(0); t-BuBrettPhos; potassium bromide In 1,4-dioxane at 130℃; for 16h; Inert atmosphere;	83%

Conditions

Conditions	Yield
With triethylphosphine for 12h; Reflux;	82.4%
With triphenylphosphine In 1,2-dichloro-benzene at 200℃;	77%
With triphenylphosphine In 1,2-dichloro-benzene Inert atmosphere; Reflux;	77%

1-bromo-3-nitrosobenzene: 1-bromo-3-nitrosobenzene

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
With cesium fluoride In acetonitrile at 20℃; regioselective reaction;	80%

: 2-azido-4'-bromo-1,1'-biphenyl

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
In tetrahydrofuran for 4h; Solvent; Inert atmosphere; Irradiation;	80%

: 2-bromo-9-(pyrimidin-2-yl)-9H-carbazole

A: 3652-90-2
2-bromo-9H-carbazole

B: 2-hydroxy-9-(2-pyrimidinyl)carbazole

Conditions

Conditions	Yield
With N1-(4-hydroxy-2,6-dimethylphenyl)-N2-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water; copper(l) chloride; sodium hydroxide In dimethyl sulfoxide at 110℃; for 24h; Schlenk technique; Inert atmosphere;	A 74% B 26%

: 3-bromodibenzo[b,d]iodol-5-ium trifluoromethanesulfonate

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
With sodium azide; copper(I) thiophene-2-carboxylate; sodium hydrogencarbonate; triphenylphosphine In N,N-dimethyl acetamide at 100℃; for 12h; Inert atmosphere; Schlenk technique;	63%
With sodium azide; copper(I) thiophene-2-carboxylate; sodium hydrogencarbonate; triphenylphosphine In N,N-dimethyl acetamide at 100℃; for 12h; Inert atmosphere; Schlenk technique;	63%

: 62532-98-3
4'-bromo-[1,1'-biphenyl]-2-amine

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; copper diacetate; Trimethylacetic acid In 1-methyl-pyrrolidin-2-one at 120℃; for 12h;	33%
Multi-step reaction with 2 steps 1.1: acetic acid; sodium nitrite / water / 1 h / 0 °C 1.2: Sandmeyer Reaction / 1 h / 0 - 20 °C / Inert atmosphere 2.1: tetrahydrofuran / 4 h / Inert atmosphere; Irradiation View Scheme
Multi-step reaction with 3 steps 1.1: hydrogenchloride; sodium nitrite / water; tetrahydrofuran / 1 h / 0 - 5 °C 1.2: 20 °C 2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 - 20 °C 3.1: copper(I) thiophene-2-carboxylate; triphenylphosphine; sodium azide; sodium hydrogencarbonate / N,N-dimethyl acetamide / 12 h / 100 °C / Inert atmosphere; Schlenk technique View Scheme

: 78863-99-7
7-bromo-2,3,4,9-tetrahydro-1H-carbazole

: 3652-90-2
2-bromo-9H-carbazole

Conditions

Conditions	Yield
With chloranil; xylene

Total:192 Page 1 of 6 1 2 3 4 5 6 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 3652-90-2

Specification

1.Introduction of 2-Bromocarbazole

The 2-Bromocarbazole with the CAS number 3652-90-2 is also called 9H-Carbazole, 2-bromo-. The systematic name is 2-bromo-9H-carbazole. Its molecular formula is C₁₂H₈BrN. This chemical is a kind of organics. It should be stored in dry and cool environment.

2.The properties of the 2-Bromocarbazole

(1)ACD/LogP: 4.59; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 4; (4)ACD/LogD (pH 7.4): 4; (5)ACD/BCF (pH 5.5): 1527; (6)ACD/BCF (pH 7.4): 1527; (7)ACD/KOC (pH 5.5): 6614; (8)ACD/KOC (pH 7.4): 6614; (9)#H bond acceptors: 1; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 15.79 Å²; (13)Index of Refraction: 1.784; (14)Molar Refractivity: 64.061 cm³; (15)Molar Volume: 152.172 cm³; (16)Polarizability: 25.396×10^-24cm³; (17)Surface Tension: 60.866 dyne/cm; (18)Enthalpy of Vaporization: 63.566 kJ/mol; (19)Vapour Pressure: 0 mmHg at 25°C.

3.Structure descriptors of 2-Bromocarbazole

(1)SMILES: Brc1ccc2c3ccccc3nc2c1
(2)InChI: InChI=1/C12H8BrN/c13-8-5-6-10-9-3-1-2-4-11(9)14-12(10)7-8/h1-7,14H
(3)InChIKey: PJRGCJBBXGNEGD-UHFFFAOYAK