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| CAS No.: | 37339-90-5 |
|---|---|
| Name: | Lentinan |
| Molecular Structure: | |
|
|
| Formula: | (C42H70O35)n |
| Molecular Weight: | 0 |
| Synonyms: | Biomoduline;LC 33; |
| EINECS: | 1806241-263-5 |
| Density: | 1.88g/cm3 |
| Boiling Point: | 1472°C at 760 mmHg |
| Flash Point: | 844°C |
| Appearance: | Yellow Fine Powder |
| PSA: | 0.00000 |
| LogP: | 0.00000 |
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Specification
The Lentinan is an organic compound with the formula (C42H70O35)n. The IUPAC name of this chemical is (2R,3R,4S,5S,6R)-2-[[(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6R)-3,5-dihydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5,6-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol. With the CAS registry number 37339-90-5, it is also named as Bromoduline. The product's category is Natural Plant Extract. Besides, it is an intravenously administered anti-cancer agent. Lentinan is one of the host-mediated anti-cancer drugs which has been shown to affect host defense immune systems. It is extracted from the mushroom.
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | > 100mg/kg (100mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. | |
| monkey | LD50 | intravenous | > 100mg/kg (100mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. | |
| mouse | LD50 | intraperitoneal | > 2500mg/kg (2500mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. | |
| mouse | LD50 | intravenous | 250mg/kg (250mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 365, 1986. | |
| mouse | LD50 | subcutaneous | > 2500mg/kg (2500mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. | |
| rabbit | LD50 | intravenous | > 100mg/kg (100mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. | |
| rat | LD50 | intraperitoneal | > 2500mg/kg (2500mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. | |
| rat | LD50 | intravenous | 250mg/kg (250mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 365, 1986. | |
| rat | LD50 | subcutaneous | > 2500mg/kg (2500mg/kg) | Drugs in Japan Vol. -, Pg. 1277, 1990. |