Products Categories
CAS No.: | 37622-90-5 |
---|---|
Name: | Ethyl pyrazole-4-carboxylate |
Article Data: | 14 |
Molecular Structure: | |
Formula: | C6H8N2O2 |
Molecular Weight: | 140.142 |
Synonyms: | Pyrazole-4-carboxylicacid, ethyl ester (7CI);4-Ethoxycarbonyl-1H-pyrazole;Ethyl1H-pyrazole-4-carboxylate;Ethyl 4-pyrazolecarboxylate; |
EINECS: | 609-452-9 |
Density: | 1.214 g/cm3 |
Melting Point: | 78-80 °C(lit.) |
Boiling Point: | 307.8 °C at 760 mmHg |
Flash Point: | 122.7 °C |
Appearance: | White to pale yellow crystalline powder |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 26-37/39 |
PSA: | 54.98000 |
LogP: | 0.58640 |
3-amino-4-pyrazolecarboxylic acid ethyl ester
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
With hydrogenchloride; acetic acid; sodium nitrite In ethanol for 1h; Heating; | 99% |
With hydrogenchloride; acetic acid; sodium nitrite In water at 0℃; for 0.5h; | 80 g |
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water at 20℃; for 16h; | 99% |
Conditions | Yield |
---|---|
With sulfuric acid for 16h; Reflux; | 97% |
With thionyl chloride at 0 - 20℃; for 3h; | 80% |
With sulfuric acid |
ethyl 2-formyl-3-oxopropanoate
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
With hydrazine dihydrochloride In ethanol at 0 - 20℃; for 32h; | 92% |
With hydrazine In ethanol at 0 - 20℃; for 24h; | 86% |
With hydrazine In ethanol at 0 - 20℃; for 17h; | 72.4% |
With hydrazine In ethanol at 20℃; for 17h; | 72.4% |
Conditions | Yield |
---|---|
With triethylamine at 100℃; for 4h; Inert atmosphere; | 90% |
ethyl 1-(hydroxymethyl)-1H-pyrazole-4-carboxylate
A
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
With potassium fluoride; 18-crown-6 ether; methyl fluorosulfonate In tetrahydrofuran Heating; |
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
With hydrazine hydrate; acetic acid |
ethyl 2-cyanoacetate
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: acetic anhydride / 5 h / 120 °C 2: hydrazine hydrate / ethanol / 8 h / 0 °C 3: sodium nitrite; acetic acid; hydrogenchloride / water / 0.5 h / 0 °C View Scheme |
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: toluene / 2 h / -50 °C 2: antimony(III) fluoride / N,N-dimethyl-formamide / 1 h / 90 °C 3: acetic acid; hydrogenchloride / 0.5 h / 0 °C View Scheme |
ethyl 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylate
4-ethoxycarbonylpyrazole
Conditions | Yield |
---|---|
With hydrogenchloride; acetic acid at 0℃; for 0.5h; Reagent/catalyst; |
What can I do for you?
Get Best Price
Empirical Formula: C6H8N2O2
Molecular Weight: 140.1399
Nominal Mass: 140 Da
Average Mass: 140.1399 Da
Monoisotopic Mass: 140.058578 Da
Index of Refraction: 1.521
Molar Refractivity: 35.18 cm3
Molar Volume: 115.3 cm3
Surface Tension: 49.2 dyne/cm
Density: 1.214 g/cm3
Flash Point: 122.7 °C
Enthalpy of Vaporization: 54.84 kJ/mol
Boiling Point: 307.8 °C at 760 mmHg
Vapour Pressure: 0.000709 mmHg at 25 °C
Melting point: 78-80 °C(lit.)
Appearance: White to pale yellow crystalline powder
Structure of Ethyl pyrazole-4-carboxylate (CAS NO.37622-90-5):
IUPAC Name: Ethyl 1H-pyrazole-4-carboxylate
Canonical SMILES: CCOC(=O)C1=CNN=C1
InChI: InChI=1S/C6H8N2O2/c1-2-10-6(9)5-3-7-8-4-5/h3-4H,2H2,1H3,(H,7,8)
InChIKey: KACZQOKEFKFNDB-UHFFFAOYSA-N
Product Category of Ethyl pyrazole-4-carboxylate (CAS NO.37622-90-5): Heterocyclic Building Blocks;Pyrazoles
Hazard Codes of Ethyl pyrazole-4-carboxylate (CAS NO.37622-90-5): Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 3
Hazard Note: Irritant
Ethyl pyrazole-4-carboxylate , its cas register number is 37622-90-5. It also can be called Ethyl 4-pyrazolecarboxylate ; and 4-Acetylpyrazole .