Products Categories
| CAS No.: | 4420-74-0 |
|---|---|
| Name: | Trimethoxysilylpropanethiol |
| Molecular Structure: | |
|
|
|
| Formula: | C6H16O3SSi |
| Molecular Weight: | 196.343 |
| Synonyms: | WD 80;Z 6062;3-mercaptopropyl trimethoxysilane;(3-Thiopropyl)trimethoxysilane;(g-Mercaptopropyl)trimethoxysilane;3-(Sulfanylpropyl)trimethoxysilane;3-(Trimethoxysilyl)-1-propanethiol;3-(Trimethoxysilyl)propanethiol;3-(Trimethoxysilyl)propyl mercaptan;3-MPTMS;3-Mercaptopropyltrimethoxylsilane;A 160 (coupling agent);A 189;AZ 6129;DynasylanMTMO;Dynasylan NTNS;GF 70;KBE 803;KBM 803P;KH 590;LS 1390;M 8500 (coupling agent);MPS-M;MPTMS;MPTS;NUCA 189;Prosil 196;SCA 903;SIM 6476.0;SiSiB PC 2300;Sila-Ace S 810;Silan GF 70;Silquest A 189;TSL 8380E;VP-Si 163; |
| EINECS: | 224-588-5 |
| Density: | 0.999 g/cm3 |
| Melting Point: | <-50 °C |
| Boiling Point: | 198 °C at 760 mmHg |
| Flash Point: | 48.9 °C |
| Solubility: | decomposes in water |
| Appearance: | white to light straw liquid clear liquid |
| Hazard Symbols: |
 Xn,  N
|
| Risk Codes: | 22-43-51/53 |
| Safety: | 24/25-36/37-61-57 |
| Transport Information: | UN 3082 9/PG 3 |
| PSA: | 66.49000 |
| LogP: | 1.18440 |
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
| Conditions | Yield |
|---|---|
| With sodium sulfide; tetrabutyl-ammonium chloride; water In toluene at 88 - 92℃; for 4h; | 93.5% |
| With N-octylpyridinium tetrafluoroborate; sodium hydrogen sulfide; triphenylethylphosphonium bromide In water at 48 - 120℃; for 3.5h; Reagent/catalyst; Inert atmosphere; | 93.32% |
| With hydrogen sulfide; sodium In methanol | |
| With hydrogen sulfide; ammonia In methanol | |
| Multi-step reaction with 2 steps 1: dodecyltrimethylphosphonium bromide / methanol / 130 - 140 °C 2: ethylenediamine; sodium methylate / 80 - 90 °C View Scheme |
- 51826-90-5
(3-bromopropyl) trimethoxysilane
- 4420-74-0
3-(trimethoxysilyl)-1-propanethiol
| Conditions | Yield |
|---|---|
| 89.4% | |
| 87.2% |
| Conditions | Yield |
|---|---|
| Stage #1: prop-2-ene-1-thiol at 62 - 64℃; for 0.5h; Inert atmosphere; Stage #2: trimethoxysilane In methanol at 72 - 75℃; for 2h; Solvent; Temperature; | 88.2% |
- 64456-54-8
S-[3-(trimethoxysilyl)propyl] ethanethioate
- 4420-74-0
3-(trimethoxysilyl)-1-propanethiol
| Conditions | Yield |
|---|---|
| With sodium methylate In methanol at 65℃; for 12h; | 88% |
| With sodium methylate In methanol |
| Conditions | Yield |
|---|---|
| With hydrogen sulfide In methanol | 79.9% |
| Conditions | Yield |
|---|---|
| With hydrogen sulfide Irradiation; |
- 2551-83-9
allyltrimethoxysilane
A
- 4420-74-0
3-(trimethoxysilyl)-1-propanethiol
B
- 35112-74-4
bis-(3-trimethoxysilylpropyl)-disulphide
C
- 29055-11-6
bis<3-(trimethoxysilyl)propyl> sulfide
| Conditions | Yield |
|---|---|
| With hydrogen sulfide under 760 Torr; for 2.5h; Irradiation; Yield given; |
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water for 1h; |
- 4420-74-0
3-(trimethoxysilyl)-1-propanethiol
| Conditions | Yield |
|---|---|
| With sodium methylate; ethylenediamine at 80 - 90℃; | 188 g |
- 4420-74-0
3-(trimethoxysilyl)-1-propanethiol
- 251091-78-8
3,12-bis-(3,5-dimethylphenyl)carbamoyl-N-allyl-deoxycholan-24-amide
| Conditions | Yield |
|---|---|
| With 2,2'-azobis(isobutyronitrile) for 20h; Addition; Heating; | 100% |
- 4422-95-11,3,5-Benzenetricarboxylic acid chloride
- 442552-50-33-[(Z)-(3-Isobutyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-(1-piperidinyl)-4H-pyrido[1,2-A]pyrimidin-4-one
- 4431-01-0Ligustilide
- 4435-53-43-Methoxybutyl acetate
- 4436-24-2(2,3-EPOXYPROPYL)BENZENE
- 4439-65-03-Hydroxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one
- 444118-90-5tert-butyldimethylsilyl (6-O-acetyl-2-azido-3,4-di-O-benzyl-2-deoxy-α-D-glucopyranosyl)-(1->4)-(methyl 3-O-benzyl-2-O-levulinoyl-β-D-glucopyranosyl)-(1->4)-3,6-di-O-acetyl-2-azido-2-deoxy-β-D-glucopyranoside
- 444151-91-11-(3-chloro-1,4-dioxo-1,4-dihydro-2-naphthalenyl)-N-cyclopentyl-4-piperidinecarboxamide
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Chemistry
IUPAC Name: 3-Trimethoxysilylpropane-1-thiol
Synonyms of Trimethoxysilylpropanethiol (CAS NO.4420-74-0): (3-Mercaptopropyl)trimethoxysilane ; (gamma-mercaptopropyl)trimethoxysilane ; 3-(Trimethoxysilyl)propyl mercaptan ; Silane, 3-mercaptopropyltrimethoxy-
CAS NO: 4420-74-0
Molecular Formula: C6H16O3SSi
Molecular Weight: 196.34
Molecular Structure: 
EINECS: 224-588-5
H bond acceptors: 3
H bond donors: 0
Freely Rotating Bonds: 7
Polar Surface Area: 52.99 Å2
Index of Refraction: 1.439
Molar Refractivity: 51.69 cm3
Molar Volume: 196.4 cm3
Surface Tension: 25.3 dyne/cm
Density: 0.999 g/cm3
Flash Point: 48.9 °C
Enthalpy of Vaporization: 41.64 kJ/mol
Boiling Point: 198 °C at 760 mmHg
Vapour Pressure: 0.518 mmHg at 25°C
Melting Point: <-50°C
Storage temp: 2-8°C
Water Solubility: decomposes
Sensitive: Air & Moisture Sensitive
Stability: Stable, but moisture sensitive - may decomposes on exposure to moist air. Incompatible with water, alcohols, strong oxidizing agents, strong acids.
Appearance: Water white to light straw liquid clear liquid
Product Categories of Trimethoxysilylpropanethiol (CAS NO.4420-74-0): Industrial/Fine Chemicals;Mercapto;Chloroalkylsilanes, etc. (Silane Coupling Agents);Functional Materials;Si (Classes of Silicon Compounds);Silane Coupling Agents;Si-O Compounds;Trialkoxysilanes;Adhesion Promoters;Coupling Agents;Mecapto Silanes;Surface Modifiers
Uses
Trimethoxysilylpropanethiol (CAS NO.4420-74-0) is used in rubber, plastic, glass fibers, coatings, adhesives and sealants products.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 633mg/kg (633mg/kg) | Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. Vol. 229, Pg. 1011, 1976. | |
| rabbit | LD50 | skin | 2140uL/kg (2.14mL/kg) | Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 15, Pg. 261, 1996. | |
| rat | LD50 | oral | 730uL/kg (0.73mL/kg) | Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 15, Pg. 261, 1996. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
Safety Information about Trimethoxysilylpropanethiol (CAS NO.4420-74-0):
Hazard Codes: 
Xn,
N
Risk Statements: 22-43-51/53
R22: Harmful if swallowed.
R43: May cause sensitization by skin contact.
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 24/25-36/37-61-57
S24/25: Avoid contact with skin and eyes.
S36/37: Wear suitable protective clothing and gloves.
S57: Use appropriate container to avoid environmental contamination.
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3082 9/PG 3
WGK Germany: 2
RTECS: TZ7800000
F: 1-10-13
TSCA: Yes
HazardClass: 9
PackingGroup: III
HS Code: 29310095
Moderately toxic by ingestion and intraperitoneal routes. Mildly toxic by skin contact. A skin irritant. When heated to decomposition it emits toxic fumes of SOx. See also MERCAPTANS and SILANE.
Specification
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustible liquid.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.
Storage: Keep away from heat and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container..