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| CAS No.: | 511-96-6 |
|---|---|
| Name: | (25R)-5ALPHA-SPIROSTAN-2ALPHA,3BETA-DIOL |
| Molecular Structure: | |
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| Formula: | C27H44 O4 |
| Molecular Weight: | 432.644 |
| Synonyms: | 5a-Spirostan-2a,3b-diol, (25R)- (8CI); Gitogenin (6CI,7CI); (25R)-5a-Spirostan-2a,3b-diol; 2a-Hydroxytigogenin; 5a,25D-Spirostan-2a,3b-diol; Digin; NSC 147752 |
| Density: | 1.16g/cm3 |
| Melting Point: | 272-273oC |
| Boiling Point: | 534.2oC at 760 mmHg |
| Flash Point: | 276.9oC |
| PSA: | 58.92000 |
| LogP: | 4.76460 |


gitogenin

| Conditions | Yield |
|---|---|
| With hydrogenchloride In 1,4-dioxane for 1h; Heating; | 88.7% |

| Conditions | Yield |
|---|---|
| With sodium hydroxide In methanol; dichloromethane at 20℃; | 85% |


gitogenin

| Conditions | Yield |
|---|---|
| With hydrogenchloride In 1,4-dioxane for 1h; Heating; | 76% |

| Conditions | Yield |
|---|---|
| With hydrogenchloride In 1,4-dioxane for 1h; Heating; | A 28.4% B 54.1% |


gitogenin

| Conditions | Yield |
|---|---|
| With hydrogenchloride In 1,4-dioxane for 1h; Heating; | 19% |

(25R)-2α,3β-diacetoxy-spirost-4-ene


gitogenin

| Conditions | Yield |
|---|---|
| With acetic acid; ethyl acetate; platinum Hydrogenation; |


gitogenin

| Conditions | Yield |
|---|---|
| With ethanol; hydrazine hydrate; diethylene glycol at 150℃; Reagens 4: Kaliumhydroxid; |

| Conditions | Yield |
|---|---|
| With tetrahydrofuran; lithium aluminium tetrahydride | |
| Multi-step reaction with 2 steps 1.1: cerium(III) chloride heptahydrate / tetrahydrofuran; methanol / 0.17 h / 20 °C 1.2: 0.5 h 2.1: sodium hydroxide / methanol; dichloromethane / 20 °C View Scheme |

(25R)-2α-hydroxy-5α-spirostan-3β-yl O-β-D-galactopyranosyl-(1 → 2)-O-[β-D-xylopyranosyl-(1 → 3)]-O-β-D-glucopyranosyl-(1 → 4)-β-D-galactopyranoside


gitogenin

| Conditions | Yield |
|---|---|
| With hydrogenchloride; ethanol |

| Conditions | Yield |
|---|---|
| at 184℃; |
