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CAS No.: | 60372-77-2 |
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Name: | ETHYL LAUROYL ARGINATE HCL |
Article Data: | 7 |
Molecular Structure: | |
Formula: | C20H41ClN4O3 |
Molecular Weight: | 421.024 |
Synonyms: | ETHYL LAUROYL ARGINATE HCL;N-ALPHA-LAUROYL-L-ARGININEETHYLESTERMONOHYDROCHLORIDE;ETHYL-N-ALPHA-LAUROYL-L-ARGINATEHYDROCHLORIDE;ETHYLLAUROYLARGINATEHYDROCHLORIDE |
Density: | 1.11[at 20℃] |
Solubility: | 247g/L at 20℃ |
PSA: | 120.79000 |
LogP: | 6.05170 |
n-dodecanoyl chloride
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
Conditions | Yield |
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With sodium hydroxide In water; ethyl acetate at 8 - 30℃; pH=7.3 - 7.5; Product distribution / selectivity; | 98.1% |
With sodium hydrogencarbonate; sodium carbonate In water; ethyl acetate at 20℃; for 3h; Green chemistry; | 96% |
Stage #1: n-dodecanoyl chloride; L‐arginine ethyl ester hydrochloride With triethylamine In tetrahydrofuran at 15 - 40℃; Stage #2: With hydrogenchloride In water at 10℃; Concentration; Solvent; Temperature; Time; Reagent/catalyst; | 94.06% |
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
Conditions | Yield |
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With hydrogenchloride for 0.5h; Time; | 96.4% |
lauric acid
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
Conditions | Yield |
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Stage #1: lauric acid With 1,1'-carbonyldiimidazole In ethyl acetate at 30℃; for 1h; Large scale; Green chemistry; Stage #2: arginine ethyl ester hydrochloride With triethylamine In ethyl acetate at 30℃; for 2h; Temperature; Large scale; Green chemistry; | 93% |
lauric acid
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
Conditions | Yield |
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With benzotriazol-1-ol; diisopropyl-carbodiimide In isopropyl alcohol at 45℃; for 30h; Reagent/catalyst; Solvent; Temperature; Green chemistry; | 8.76 g |
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
sodium acetate
Nα-lauroyl-L-arginine ethyl ester acetate
Conditions | Yield |
---|---|
In water at 75 - 80℃; for 6h; Product distribution / selectivity; | 98.5% |
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
Sodium laurate
Nα-lauroyl-L-arginine ethyl ester laurate
Conditions | Yield |
---|---|
In water at 80 - 85℃; for 0.5h; | 96.5% |
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
glycolic Acid
Conditions | Yield |
---|---|
Stage #1: Nα-lauroyl-L-arginine ethyl ester monohydrochloride With pyridine In acetic acid butyl ester at 60℃; for 1h; Stage #2: glycolic Acid at 60℃; for 3h; Concentration; Reagent/catalyst; Solvent; Temperature; | 95.2% |
Conditions | Yield |
---|---|
With sodium hydroxide In methanol; water at 90℃; for 2h; | 5 g |
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
sodium carbonate
Conditions | Yield |
---|---|
With sodium hydroxide In water at 90℃; for 2h; | 4 g |
Nα-lauroyl-L-arginine ethyl ester monohydrochloride
sodium nicotinate
Conditions | Yield |
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In water at 90℃; for 2h; | 7.6 g |