CAS No.616-82-0,4-Hydroxy-3-nitrobenzoic acid Suppliers

Products Categories

Pharmaceutical (55)
Organic Chemicals (20)
Others (8)
Reagent (4)
Materials (1)

Basic Information

Molecular Structure:
CAS No.:	616-82-0
Name:	4-Hydroxy-3-nitrobenzoic acid
Article Data:	66

Formula:	C₇H₅NO₅
Molecular Weight:	183.12
Synonyms:	3-Nitro-4-hydroxybenzoicacid;4-Carboxy-2-nitrophenol;NSC 78436;p-Hydroxy-m-nitrobenzoic acid;3-Nitro-4-hydroxybenzoic acid;
EINECS:	210-494-1
Density:	1.632 g/cm³
Melting Point:	183-186 °C(lit.)
Boiling Point:	354.304 °C at 760 mmHg
Flash Point:	162.528 °C
Appearance:	yellow to light brown powder
Hazard Symbols:	Xn,Xi
Risk Codes:	36/37/38
Safety:	26-37/39-24/25-36
PSA:	103.35000
LogP:	1.52180

Synthetic route

: 99-96-7
4-hydroxy-benzoic acid

: 616-82-0
3-nitro-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With magnesium(II) nitrate hexahydrate; AMA at 20℃; for 1.5h; Neat (no solvent); regioselective reaction;	98%
With dimethylbromosulphonium bromide; tetrabutylammonium nitrite In acetonitrile at 20℃; for 2h; regioselective reaction;	93%
With trichloroisocyanuric acid; silica gel; sodium nitrite In dichloromethane at 20℃; for 0.333333h;	87%

: 96-99-1
4-chloro-3-nitrobenzoate

: 616-82-0
3-nitro-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With water; sodium hydroxide at 100℃;	98%
With sodium hydroxide In water at 95℃; for 10h;	91.83%
With sodium hydroxide In water	430 g (90 %)

: 453-71-4
3-nitro-4-fluorobenzoic acid

: 616-82-0
3-nitro-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With acetylhydroxamic acid; potassium carbonate In dimethyl sulfoxide at 80℃; for 1h; Sealed tube;	93%

: 99-96-7
4-hydroxy-benzoic acid

A: 100-02-7
4-nitro-phenol

B: 616-82-0
3-nitro-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With ammonium cerium(IV) nitrate In acetonitrile at 20℃; for 0.333333h;	A 10% B 84%

: 99-96-7
4-hydroxy-benzoic acid

A: 51-28-5
2,4-Dinitrophenol

B: 616-82-0
3-nitro-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With ammonium cerium(IV) nitrate In acetonitrile at 60 - 70℃; for 0.25h;	A 45% B 50%
With ammonium cerium(IV) nitrate In acetonitrile at 60 - 70℃; for 0.25h;	A 50% B 50%
With chloroform; nitric acid

: 619-57-8
p-hydroxybenzamide

A: 616-82-0
3-nitro-4-hydroxybenzoic acid

B: 74230-08-3
2-nitro-4-hydroxybenzoic acid

C: 99-96-7
4-hydroxy-benzoic acid

Conditions

Conditions	Yield
With acetic acid; isopentyl nitrite at 80℃; for 21h; Inert atmosphere;	A 39% B 43% C 13%

...Expand

: 99-50-3
3,4-Dihydroxybenzoic acid

A: 51-28-5
2,4-Dinitrophenol

B: 616-82-0
3-nitro-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With diethyl ether; cis-nitrous acid

: 623-11-0
1-methyl-4-nitrosobenzene

: 528-45-0
3,4-dinitrobenzoic acid

: 616-82-0
3-nitro-4-hydroxybenzoic acid

: 623-11-0
1-methyl-4-nitrosobenzene

: (4-methoxycarbonyl-2-nitro-phenoxy)-acetic acid

: 616-82-0
3-nitro-4-hydroxybenzoic acid

: 623-11-0
1-methyl-4-nitrosobenzene

: 476313-40-3
4-methoxycarbonylmethoxy-3-nitro-benzoic acid

: 616-82-0
3-nitro-4-hydroxybenzoic acid

Total:76 Page 1 of 2 1 2 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 616-82-0

Specification

The 4-Hydroxy-3-nitrobenzoic acid, with the CAS registry number 616-82-0, is also known as 3-Nitro-4-hydroxybenzoic acid. It belongs to the product categories of Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Organic acids; C7; Carbonyl Compounds;Carboxylic Acids. Its EINECS number is 210-494-1. This chemical's molecular formula is C₇H₅NO₅ and molecular weight is 183.12. What's more, its systematic name is Ethyl hydrazinecarboxylate. Its storage temperature is 0°C. This chemical is used as a pharmaceutical intermediate.

Physical properties of 4-Hydroxy-3-nitrobenzoic acid are: (1)ACD/LogP: 1.904; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.08; (4)ACD/LogD (pH 7.4): -1.89; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 3.91; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 6; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 103.35 Å²; (13)Index of Refraction: 1.664; (14)Molar Refractivity: 41.61 cm³; (15)Molar Volume: 112.234 cm³; (16)Polarizability: 16.495×10^-24cm³; (17)Surface Tension: 84.1 dyne/cm; (18)Density: 1.632 g/cm³; (19)Flash Point: 162.528 °C; (20)Enthalpy of Vaporization: 63.243 kJ/mol; (21)Boiling Point: 354.304 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When using it, you must avoid contact with skin and eyes. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: O=[N+]([O-])c1cc(ccc1O)C(=O)O
(2)Std. InChI: InChI=1S/C7H5NO5/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3,9H,(H,10,11)
(3)Std. InChIKey: QRYSWXFQLFLJTC-UHFFFAOYSA-N