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6989-98-6

Basic Information
CAS No.: 6989-98-6
Name: (+)-TUBOCURARINE CHLORIDE PENTAHYDRATE
Molecular Structure:
Molecular Structure of 6989-98-6 ((+)-TUBOCURARINE CHLORIDE PENTAHYDRATE)
Formula: C37H41 N2 O6 . Cl H . Cl . 5 H2 O
Molecular Weight: 785.84
Synonyms: Tubocuraranium,7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, chloride, hydrochloride,pentahydrate;(+)-Tubocurarine chloride hydrochloride pentahydrate;Tubarinepentahydrate;d-Tubocurarine dichloride pentahydrate;
EINECS: 200-356-9
Density: 1.2074 (rough estimate)
Melting Point: 275-280 °C (dec.)(lit.)
Solubility: Soluble in water to 50mg/ml, with warming as needed. Also soluble in ethanol or methanol
Hazard Symbols: T
Risk Codes: 25
Safety: Poison by ingestion, subcutaneous, and intravenous routes. Human toxicity: Large doses and overdoses may cause respiratory paralysis and hypotension. When heated to decomposition it emits very toxic fumes of NOx and Cl.
PSA: 126.77000
LogP: 4.08220
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Chemistry

Chemical Name: (+)-Tubocurarine chloride pentahydrate
CAS No.: 6989-98-6
EINECS: 200-356-9
RTECS: YO5100000
Molecular Formula: C37H52Cl2N2O11
Molecular Weight: 771.72 g/mol
Melting Point: 275-280 °C (dec.)(lit.)
Storage temp.: 2-8°C
Following is the structure of d-Tubocurarine chloride penta-hydrate (6989-98-6):


Product Categories about d-Tubocurarine chloride penta-hydrate (6989-98-6) are Alkaloids ; Biochemistry ; Isoquinoline Alkaloids ; Complex MoleculesEnzyme Inhibitors ; Asymmetric Synthesis ; Chiral Building Blocks ; Enzyme Inhibitors by Type
The chemical synonymous of d-Tubocurarine chloride penta-hydrate (6989-98-6) are Dichloride,pentahydrate,(+)-tubocurarin ; Tubocurarine chloride ; Tubocurarine hydroehloride ; (+)-Tubocurarine chloride pentahydrate ; d-Tubocurarine chloride pentahydrate ; (+)-Tubocurarine chloride muscle relaxan t ; Tubarine pentahydrate. ; Tubocurarin-dichloride, pentahydrat

Toxicity Data With Reference

1.    

orl-mus LD50:150 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.
2.    

scu-mus LD50:600 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 100 (1950),333.
3.    

ivn-mus LD50:130 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),388.
4.    

orl-cat LDLo:18 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.
5.    

ivn-cat LD50:400 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.
6.    

ivn-rbt LD50:146 µg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.

Safety Profile

Poison by ingestion, subcutaneous, and intravenous routes. Human toxicity: Large doses and overdoses may cause respiratory paralysis and hypotension. When heated to decomposition it emits very toxic fumes of NOx and Cl.
Hazard Codes:
T: Toxic
Risk Statements about d-Tubocurarine chloride penta-hydrate (6989-98-6):
R25 Toxic if swallowed.
Safety Statements about d-Tubocurarine chloride penta-hydrate (6989-98-6):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.