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73895-98-4

Basic Information
CAS No.: 73895-98-4
Name: 2-Bromoo-4-methyl-6-aminopyridine
Article Data: 6
Molecular Structure:
Molecular Structure of 73895-98-4 (2-Bromoo-4-methyl-6-aminopyridine)
Formula: C6H7 Br N2
Molecular Weight: 187.039
Synonyms: 4-Picoline,2-amino-6-bromo- (7CI); 6-Amino-2-bromo-4-methylpyridine;6-Bromo-4-methylpyridin-2-ylamine
Density: 1.593g/cm3
Melting Point: 115 °C
Boiling Point: 293.675°C at 760 mmHg
Flash Point: 131.41°C
PSA: 38.91000
LogP: 2.31590
Synthetic route
72060-94-7

1,3-dicyano-2-methyl-2-hydroxypropane

73895-98-4

6-bromo-4-methylpyridine-2-amine

Conditions
ConditionsYield
With sodium hydroxide; hydrogen bromide In acetic acid; ethyl acetate66%
With hydrogen bromide; acetic acid at 20℃; for 2h;
598-09-4

2-chloromethyl-2-methyloxiran

72060-94-7

1,3-dicyano-2-methyl-2-hydroxypropane

73895-98-4

6-bromo-4-methylpyridine-2-amine

Conditions
ConditionsYield
With sodium hydroxide; hydrogen bromide In hydrogenchloride; water; acetic acid; ethyl acetate
108-24-7

acetic anhydride

73895-98-4

6-bromo-4-methylpyridine-2-amine

263894-96-8

N-(6-bromo-4-methyl-pyridin-2-yl)-acetamide

Conditions
ConditionsYield
With pyridine; dmap89%
73895-98-4

6-bromo-4-methylpyridine-2-amine

824-94-2

p-methoxybenzyl chloride

6-bromo-N,N-bis[(4-methoxyphenyl)methyl]-4-methylpyridin-2-amine

Conditions
ConditionsYield
Stage #1: 6-bromo-4-methylpyridine-2-amine With sodium hydride In N,N-dimethyl-formamide at 0 - 25℃; for 1h;
Stage #2: p-methoxybenzyl chloride In N,N-dimethyl-formamide at 25℃; for 2h;
87.5%
1227068-84-9

2-(4,4-difluorocyclohex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

73895-98-4

6-bromo-4-methylpyridine-2-amine

6-(4,4-difluorocyclohex-1-en-1-yl)-4-methylpyridin-2-amine

Conditions
ConditionsYield
With potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 100℃; for 16h;83%
73895-98-4

6-bromo-4-methylpyridine-2-amine

110-13-4

2,5-hexanedione

771530-89-3

2-bromo-6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene at 150℃; for 1h; Microwave irradiation;82%
With toluene-4-sulfonic acid In toluene for 1.5h; Paal-Knorr reaction; Heating;
With sodium acetate; acetic acid In toluene for 48h; Heating / reflux;
73895-98-4

6-bromo-4-methylpyridine-2-amine

2032-35-1

Bromoacetaldehyde diethyl acetal

5-bromo-7-methylimidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; ethyl acetate76%
106-42-3

para-xylene

73895-98-4

6-bromo-4-methylpyridine-2-amine

1644526-66-8

1-bromo-3,6,9-trimethylpyrido[1,2-a]benzimidazole

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene at 40℃; for 12h; regioselective reaction;76%
24424-99-5

di-tert-butyl dicarbonate

73895-98-4

6-bromo-4-methylpyridine-2-amine

1206249-13-9

tert-butyl (6-bromo-4-methylpyridin-2-yl)carbamate

Conditions
ConditionsYield
With triethylamine In tert-butyl alcohol at 20℃; for 24h;76%
107-20-0

2-chloroethanal

73895-98-4

6-bromo-4-methylpyridine-2-amine

5-bromo-7-methylimidazo[1,2-a]pyridine

Conditions
ConditionsYield
In ethanol for 20h; Reflux;75%
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