CAS No.76-66-4,Rhynchophylline Suppliers

Products Categories

Plant Extract (74)
Pharmaceutical (51)
Others (14)
Organic Chemicals (13)
Reagent (1)

Basic Information

Molecular Structure:
CAS No.:	76-66-4
Name:	Rhynchophylline
Article Data:	7

Formula:	C₂₂H₂₈N₂O₄
Molecular Weight:	384.475
Synonyms:	Corynoxan-16-carboxylicacid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7b,16E,20a)-;Rhyncophylline (6CI,7CI,8CI);Mitrinermine;NSC 21731;Rhynchophyllin;Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-a-(methoxymethylene)-2-oxo-,methyl ester, [1'R-[1'a,6'b,7'a(E),8'ab]]-;18.beta.-Glycyrrhetic acid;Mitrinermin;
Density:	1.23 g/cm³
Melting Point:	216°; mp 197-199° (Ban et al., loc. cit.)
Boiling Point:	560.8 °C at 760 mmHg
Flash Point:	293 °C
Appearance:	Red brown or white fine powder
PSA:	67.87000
LogP:	2.77610

Raw Materials

630-94-4

61-54-1

Country:
Business Type:
All

Lab/Research institutions

Trading Company

Manufacturers

Other
Certificate:
Manufacturer

Enterprise Authentication

ISO

GMP

FDA

HALAL

Display:default sort
Suppiers of more reward points first

New supplier

Total:98 Page 1 of 3 1 2 3 Next>>

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 76-66-4

Specification

The Mitrinermin, with the CAS registry number 76-66-4, has the systematic name of methyl (7β,16E,20α)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate. It belongs to the product category of Alkaloids. And the molecular formula of the chemical is C₂₂H₂₈N₂O₄.

The characteristics of Mitrinermin are as followings: (1)ACD/LogP: 3.31; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.57; (4)ACD/LogD (pH 7.4): 2.19; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 14.47; (7)ACD/KOC (pH 5.5): 2.71; (8)ACD/KOC (pH 7.4): 112.79; (9)#H bond acceptors: 6; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 59.08 Å²; (13)Index of Refraction: 1.596; (14)Molar Refractivity: 105.57 cm³; (15)Molar Volume: 310.2 cm³; (16)Polarizability: 41.85×10^-24cm³; (17)Surface Tension: 52.2 dyne/cm; (18)Density: 1.23 g/cm³; (19)Flash Point: 293 °C; (20)Enthalpy of Vaporization: 84.35 kJ/mol; (21)Boiling Point: 560.8 °C at 760 mmHg; (22)Vapour Pressure: 1.32E-12 mmHg at 25°C.

Uses of Mitrinermin: It is always used to treat hypertension, and it is also helpful in treating high blood pressure in I and II period. What's more, it also can improve deformation capacity of red blood cells, and restrain the adverse factors on the erythrocyte deformation ability damage.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: O=C2Nc1ccccc1[C@]24[C@H]3N(C[C@@H]([C@@H](C(=C\OC)/C(=O)OC)C3)CC)CC4
(2)InChI: InChI=1/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22+/m0/s1
(3)InChIKey: DAXYUDFNWXHGBE-KAXDATADBC

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	134mg/kg (134mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 94, Pg. 17, 1989.
mouse	LD50	intravenous	105mg/kg (105mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 94, Pg. 17, 1989.