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| CAS No.: | 8001-28-3 |
|---|---|
| Name: | CROTON OIL |
| Molecular Structure: | |
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| Formula: | Unspecified |
| Molecular Weight: | 0 |
| Synonyms: | Croton oil;CCRIS 648;Croton resin;Croton tiglium L. oil;Crotonoel;Crotonoel [German];Oils, croton;Oleum tiglii; |
| EINECS: | 310-127-6 |
| Density: | 0.94 g/mL at 25 °C(lit.) |
| Flash Point: | 74 °C |
| Solubility: | Soluble in alcohol, chloroform, ether, and petroleum ether. Insoluble in water. |
| Safety: | 23-24/25 |
| PSA: | 0.00000 |
| LogP: | 0.00000 |
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Specification
The Croton oil, with the CAS registry number 8001-28-3,is also known as Croton tiglia seed oil; Croton tiglium seed oil. It belongs to the product categories of Biochemicals and Reagents;Lipids;Oils. Its chemical's molecular formula is Unspecified. What's more,Its systematic name is Croton oil.It is a colorless liquid with an unpleasant odor which is a vesicant and skin irritant used as pharmacologic standard for skin inflammation and allergy and causes skin cancer. It was formerly used as an emetic and cathartic with frequent mortality. It is toxic and a strong skin irritant.When you use it,do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) and avoid contact with skin and eyes .
The toxicity data of Croton oil are as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| frog | LD50 | intraperitoneal | 60mg/kg (60mg/kg) | Zeitschrift fuer Krebsforschung. Vol. 65, Pg. 325, 1963. | |
| frog | LD50 | parenteral | 60mg/kg (60mg/kg) | Zeitschrift fuer Krebsforschung. Vol. 65, Pg. 325, 1963. | |
| mouse | LD70 | subcutaneous | 3740ug/kg (3.74mg/kg) | Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 7, Pg. 1276, 1961. | |
| mouse | LDLo | intraperitoneal | 1mg/kg (1mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972. |