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Basic Information
CAS No.: 82-54-2
Name: cotarnine
Molecular Structure:
Molecular Structure of 82-54-2 (cotarnine)
Formula: C12H15 N O4
Molecular Weight: 237.255
Synonyms: Cotarnine(7CI,8CI)
Density: 1.321g/cm3
Melting Point: 132.5°C (rough estimate)
Boiling Point: 365.3°Cat760mmHg
Flash Point: 174.7°C
Safety: Poison by an unspecified route. When heated to decomposition it emits toxic fumes of NOx.
PSA: 51.16000
LogP: 0.84060
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Chemistry

Product Name: cotarnine (CAS NO.82-54-2)


Molecular Formula: C12H15NO4
Molecular Weight: 237.28g/mol
Mol File: 82-54-2.mol
Einecs: 201-429-8
Boiling point: 365.3 °C at 760 mmHg
Flash Point: 174.7 °C
Density: 1.321 g/cm3
Surface Tension: 51.2 dyne/cm
Enthalpy of Vaporization: 64.52 kJ/mol
Vapour Pressure: 5.61E-06 mmHg at 25°C
XLogP3-AA: 1
H-Bond Donor: 1
H-Bond Acceptor: 5

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo unreported 200mg/kg (200mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
frog LDLo unreported 40mg/kg (40mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
mouse LDLo subcutaneous 400mg/kg (400mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Pharmazie. Vol. 15, Pg. 111, 1960.
rabbit LDLo intravenous 180mg/kg (180mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Pharmazie. Vol. 15, Pg. 111, 1960.
rabbit LDLo unreported 180mg/kg (180mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.

Safety Profile

Poison by an unspecified route. When heated to decomposition it emits toxic fumes of NOx.

Specification

 Cotarnine ,its CAS NO. is 82-54-2,the synonyms is Cotarnine (base and/or unspecified salts) ; 1-Hydroxy-8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline ; 4-27-00-06448 (Beilstein Handbook Reference) ; 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-ol ; 1,3-Dioxolo(4,5-g)isoquinolin-5-ol,5,6,7,8-tetrahydro-4-methoxy-6-methyl- (9CI) ; 5,6,7,8-Tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-ol .