Products Categories
CAS No.: | 833486-94-5 | ||||||||
---|---|---|---|---|---|---|---|---|---|
Name: | 4-AMINO-3-NITROPHENYLBORONIC ACID, PINACOL ESTER | ||||||||
Molecular Structure: | |||||||||
Formula: | C12H17 B N2 O4 | ||||||||
Molecular Weight: | 264.089 | ||||||||
Synonyms: | 2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline;[2-Nitro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]amine | ||||||||
Density: | 1.2g/cm3 | ||||||||
Melting Point: |
157.1-172.4 °C |
||||||||
Boiling Point: | 404°C at 760 mmHg | ||||||||
Flash Point: | 198.1°C | ||||||||
Hazard Symbols: | |||||||||
Risk Codes: | 36/37/38 | ||||||||
Safety: |
|
||||||||
PSA: | 90.30000 | ||||||||
LogP: | 2.58060 |
4-Bromo-2-nitroaniline
bis(pinacol)diborane
4-amino-3-nitrophenylboronic acid pinacol ester
Conditions | Yield |
---|---|
With potassium acetate; palladium diacetate In N,N-dimethyl-formamide at 85℃; for 5h; | 92% |
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In 1,4-dioxane for 2h; Inert atmosphere; | 91.9% |
With potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In 1,4-dioxane at 85℃; | 86% |
4-Chloro-2-nitroaniline
bis(pinacol)diborane
4-amino-3-nitrophenylboronic acid pinacol ester
Conditions | Yield |
---|---|
With potassium phosphate tribasic heptahydrate; chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); XPhos In ethanol at 20℃; for 1.5h; | 63% |
4-amino-3-nitrophenylboronic acid pinacol ester
4,6-dichloro-5-methoxypyrimidine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane; water at 80℃; for 3h; Suzuki Coupling; | 100% |
4-amino-3-nitrophenylboronic acid pinacol ester
2-chloro-4,6-diphenyl-1,3,5-triazine
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene for 12h; Reflux; | 100% |
4-amino-3-nitrophenylboronic acid pinacol ester
2-bromo-5-methoxy-1,3-benzothiazole
2-(4'-amino-3-nitrophenyl)-6-methoxybenzothiazole
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-nitrophenylboronic acid pinacol ester; 2-bromo-6-methoxy-1,3 benzothiazole With potassium carbonate In water; N,N-dimethyl-formamide for 1h; Suzuki-Miyaura Coupling; Inert atmosphere; Stage #2: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In water; N,N-dimethyl-formamide at 80℃; for 2h; Suzuki-Miyaura Coupling; Inert atmosphere; | 99% |
4-amino-3-nitrophenylboronic acid pinacol ester
6-hydroxy-2-bromo-benzothiazole
2-(4'-amino-3-nitrophenyl)-6-hydroxybenzothiazole
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-nitrophenylboronic acid pinacol ester; 6-hydroxy-2-bromo-benzothiazole With potassium carbonate In water; N,N-dimethyl-formamide for 1h; Suzuki-Miyaura Coupling; Inert atmosphere; Stage #2: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In water; N,N-dimethyl-formamide at 80℃; for 1.5h; Temperature; Time; Suzuki-Miyaura Coupling; Inert atmosphere; | 98% |
4-amino-3-nitrophenylboronic acid pinacol ester
4-iodo-5-methyl-1,2-oxazole
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-nitrophenylboronic acid pinacol ester; 4-iodo-5-methyl-1,2-oxazole With caesium carbonate In 1,4-dioxane; water at 0.2℃; for 0.25h; Stage #2: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In 1,4-dioxane; water at 100℃; for 0.5h; Inert atmosphere; | 96% |
4-amino-3-nitrophenylboronic acid pinacol ester
2,7-dibromo-2',7'-di-[5-[3,4-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]-1,3,4-oxadiazole-2-yl]-9,9'-spirobifluorene
2,7-di-(4-amino-3-nitrophenyl)-2',7'-di-[5-[3,4-bis[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]phenyl]-1,3,4-oxadiazole-2-yl]-9,9'-spirobifluorene
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In tetrahydrofuran; water for 12h; Suzuki coupling; Inert atmosphere; Reflux; | 94% |
4-amino-3-nitrophenylboronic acid pinacol ester
(S)-3-((S)-1-(4-bromophenyl)ethyl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one
3-[(S)-1-(4'-amino-3'-nitrobiphenyl-4-yl)ethyl]-(S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-[1,3]oxazinan-2-one
Conditions | Yield |
---|---|
Stage #1: 4-amino-3-nitrophenylboronic acid pinacol ester; (S)-3-((S)-1-(4-bromophenyl)ethyl)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-1,3-oxazinan-2-one With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In water at 100℃; Inert atmosphere; Stage #2: With citric acid In water pH=5 - 6; | 93% |
4-amino-3-nitrophenylboronic acid pinacol ester
methyl 3-[methyl(propan-2-yl)amino]-2-[(trifluoromethane)sulfonyloxy]quinoxaline-6-carboxylate
methyl 2-(4-amino-3-nitrophenyl)-3-(isopropyl(methyl)amino)quinoxaline-6-carboxylate
Conditions | Yield |
---|---|
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water at 90℃; for 0.666667h; Inert atmosphere; | 93% |