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| CAS No.: | 86-40-8 |
|---|---|
| Name: | 3,6-DIAMINO-10-METHYLACRIDINIUM CHLORIDE |
| Molecular Structure: | |
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|
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| Formula: | C14H14 N3 . Cl |
| Molecular Weight: | 259.738 |
| Synonyms: | 3,6-Diamino-10-methylacridiniumchloride (7CI); Acridinium, 3,6-diamino-10-methyl-, chloride (8CI,9CI); 2,8-Diamino-10-methylacridiniumchloride; 3,6-Diamino-N-methylacridinium chloride; Avlon; Burnol; C.I. 46000;Chromoflavine |
| Safety: | A human poison by intravenous route. Poison experimentally by intraperitoneal, intravenous, and subcutaneous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and Cl−. |
| PSA: | 55.92000 |
| LogP: | 0.14830 |
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Chemistry
Product Name: Xanthacridine (CAS NO.86-40-8)
Molecular Formula: C14H14ClN3
Molecular Weight: 259.7341g/mol
Mol File: 86-40-8.mol
Einecs: 201-668-8
H-Bond Donor: 2
H-Bond Acceptor: 3
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| bird - wild | LD50 | oral | 56200ug/kg (56.2mg/kg) | Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. | |
| cat | LDLo | intravenous | 7353ug/kg (7.353mg/kg) | SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Lancet. Vol. 196, Pg. 838, 1919. |
| dog | LDLo | intravenous | 25mg/kg (25mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 38, Pg. 145, 1930. |
| frog | LDLo | subcutaneous | 800mg/kg (800mg/kg) | PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 12, Pg. 195, 1921. |
| guinea pig | LDLo | intraperitoneal | 250mg/kg (250mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935. | |
| guinea pig | LDLo | intravenous | 40mg/kg (40mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935. | |
| guinea pig | LDLo | subcutaneous | 250mg/kg (250mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935. | |
| human | LDLo | intravenous | 1500ug/kg (1.5mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 38, Pg. 145, 1930. | |
| mammal (species unspecified) | LD50 | intraperitoneal | 65mg/kg (65mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 217, 1944. | |
| mouse | LD50 | intravenous | 40mg/kg (40mg/kg) | British Journal of Experimental Pathology. Vol. 28, Pg. 1, 1947. | |
| mouse | LD50 | subcutaneous | 14mg/kg (14mg/kg) | British Journal of Experimental Pathology. Vol. 28, Pg. 1, 1947. | |
| mouse | LDLo | intraperitoneal | 11mg/kg (11mg/kg) | Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972. | |
| quail | LD50 | oral | > 100mg/kg (100mg/kg) | Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982. | |
| rabbit | LDLo | intravenous | 25mg/kg (25mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Pharmacology and Experimental Therapeutics. Vol. 38, Pg. 145, 1930. |
Consensus Reports
Reported in EPA TSCA Inventory.
Safety Profile
A human poison by intravenous route. Poison experimentally by intraperitoneal, intravenous, and subcutaneous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and Cl−.
Specification
Xanthacridine ,its CAS NO. is 86-40-8,the synonyms is Timtec-bb sbb003092 ; 2 8-Diamino-10-methylacridinium chloride hydrochloride ; 3,6-Diamino-10-methylacridinium chloride ; Labotest-bb lt00244810 ; 3,6-Diamino-10-methyl-acridiniuchloride ; Burnol ; Acridinium, 3,6-diamino-10-methyl-, chloride ; Chromoflavine .