Products Categories
CAS No.: | 877-37-2 |
---|---|
Name: | 2-bromo-4-chloropropiophenone |
Article Data: | 71 |
Molecular Structure: | |
Formula: | C9H8 Br Cl O |
Molecular Weight: | 247.519 |
Synonyms: | Propiophenone,2-bromo-4'-chloro- (7CI,8CI); 2-Bromo-1-(4-chlorophenyl)-1-propanone;2-Bromo-4'-chloropropiophenone; a-Bromo-4'-chloropropiophenone; a-Bromo-p-chloropropiophenone |
Density: | 1.518g/cm3 |
Melting Point: | 77-79 °C(Solv: ligroine (8032-32-4)) |
Boiling Point: | 296.7°C at 760 mmHg |
Flash Point: | 133.2°C |
PSA: | 17.07000 |
LogP: | 3.30610 |
Conditions | Yield |
---|---|
With bromine at 20℃; for 0.333333h; | 100% |
Stage #1: 4'-chloropropiophenone With bromine In methanol at 20℃; for 0.166667h; Stage #2: With hydrogen bromide In methanol; water for 110h; Inert atmosphere; | 98% |
With bromine; hydrogen bromide In methanol at 20℃; for 110h; Inert atmosphere; | 98% |
Conditions | Yield |
---|---|
Stage #1: chlorobenzene With aluminum (III) chloride In dichloromethane at 10 - 15℃; for 1h; Stage #2: α-bromopropionyl bromide In dichloromethane at 20℃; for 16h; Stage #3: With water In dichloromethane at 0℃; | 95.5% |
Stage #1: chlorobenzene With aluminum (III) chloride In dichloromethane at 10 - 15℃; for 1h; Stage #2: α-bromopropionyl bromide In dichloromethane at 20℃; for 16h; | 95.5% |
With aluminium trichloride at 0℃; for 1.5h; | 91% |
With aluminum (III) chloride In dichloromethane at 0 - 20℃; for 1h; Concentration; Inert atmosphere; | 74% |
Conditions | Yield |
---|---|
With aluminium trichloride |
Conditions | Yield |
---|---|
With hydrogen bromide |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: carbon disulfide; AlCl3 / Erwaermen des Reaktionsgemisches 2: acetic acid; bromine View Scheme | |
Multi-step reaction with 2 steps 1: aluminum (III) chloride / dichloromethane 2: bromine / dichloromethane View Scheme |
triphenylphosphine
A
triphenyl[1-(4-chlorophenyl)-1-oxo-2-propyl]-phosphonium bromide
B
2-bromo-1-(4-chlorophenyl)-1-propanone
Conditions | Yield |
---|---|
In acetonitrile |
Conditions | Yield |
---|---|
With bromine In chloroform |
Conditions | Yield |
---|---|
In diethyl ether; bromine |
4'-chloropropiophenone
2-(2,6-dichloro-phenyl)-6-(4,5-diphenyl-oxazol-2-yl)-1H-benzoimidazole
2-bromo-1-(4-chlorophenyl)-1-propanone
Conditions | Yield |
---|---|
With hydrogen bromide; bromine In dichloromethane for 0.25h; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: iodine; magnesium / diethyl ether / Inert atmosphere 1.2: 6 h / Reflux 1.3: Heating 2.1: bromine / diethyl ether / 20 °C / Cooling with ice View Scheme |