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Basic Information
CAS No.: 97-07-4
Name: 4-Chloro-3-nitrophenyl methyl sulfone
Molecular Structure:
Molecular Structure of 97-07-4 (4-Chloro-3-nitrophenyl methyl sulfone)
Formula: C7H6ClNO4S
Molecular Weight: 235.648
Synonyms: Sulfone,4-chloro-3-nitrophenyl methyl (6CI,7CI,8CI);1-Chloro-4-(methylsulfonyl)-2-nitrobenzene;2-Chloro-5-(methylsulfonyl)-1-nitrobenzene;3-Nitro-4-chlorophenyl methyl sulfone;4-(Methylsulfonyl)-2-nitrochlorobenzene;NSC 25818;
EINECS: 202-557-7
Density: 1.52 g/cm3
Melting Point: 125-129 ºC
Boiling Point: 414.179 °C at 760 mmHg
Flash Point: 204.288 °C
Hazard Symbols: Xn
Risk Codes: R20/21/22; R36/37/38
PSA: 88.34000
LogP: 3.25570
Synthetic route
98-57-7

4-chlorophenyl methyl sulfone

97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 25℃; for 2h;99.7%
(nitration);
98-60-2

4-chlorobenzenesulfonyl chloride

97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium sulfite; sodium hydrogencarbonate / water / 4 h / 75 °C
1.2: 15 h / 105 - 107 °C
2.1: sulfuric acid; nitric acid / 2 h / 25 °C
View Scheme
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

917562-22-2

C12H13NO8S

Conditions
ConditionsYield
Stage #1: malonic acid dimethyl ester With potassium tert-butylate In tert-butyl alcohol
Stage #2: 1-chloro-4-methanesulfonyl-2-nitrobenzene In tert-butyl alcohol at 20℃; for 15h; Heating / reflux;
100%
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

6320-02-1

2-bromothiophenol

2'-Brom-2-nitro-4-methylsulfonyl-diphenylsulfid

Conditions
ConditionsYield
In ethanol at 40 - 80℃; for 0.5h;99%
With sodium hydroxide
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

105-34-0

methyl 2-cyanoacetate

methyl 2-cyano-2-(4-(methylsulfonyl)-2-nitrophenyl)acetate

Conditions
ConditionsYield
With sodium hydroxide In dimethyl sulfoxide at 60℃; for 1h;96%
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

616-30-8, 13552-31-3

3-Amino-1,2-propanediol

120381-40-0

4-(β,γ-dihydroxypropylamino-3-nitro)phenyl methyl sulfone

Conditions
ConditionsYield
In dimethyl sulfoxide95%
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

2557-78-0

2-fluorothiophenol

129846-91-9

2-(2-fluorophenylthio)-5-(methylsulfonyl)nitrobenzene

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 4h;95%
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

693-05-0

N-(2-cyanoethyl)-N-methylamine

81689-46-5

3-[(4-Methanesulfonyl-2-nitro-phenyl)-methyl-amino]-propionitrile

Conditions
ConditionsYield
In butan-1-ol at 118℃; for 2h;91%
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

108-88-3

toluene

C14H14ClNO2S

Conditions
ConditionsYield
With tert.-butylhydroperoxide; hydrogen In water; toluene at 160℃; under 30003 Torr; for 36h; Autoclave;84%
97-07-4

1-chloro-4-methanesulfonyl-2-nitrobenzene

39930-15-9

(3-chlorophenyl)(pyridin-2-yl)methanamine

(rac)-N-((3-chlorophenyl)(pyridin-2-yl)methyl)-4-(methylsulfonyl)-2-nitroaniline

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl acetamide at 130℃; for 0.5h; Sealed tube; Microwave irradiation;83%
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  • Casno:

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  • 97-07-4  C7H6ClNO4S  4-Chloro-3-nitrophenyl methyl sulfone  CAS NO.97-07-4

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Chemistry

Molecular Structure:

Molecular Formula: C7H6ClNO4S
Molecular Weight: 235.6448
IUPAC Name: 1-Chloro-4-methylsulfonyl-2-nitrobenzene
Synonyms of 4-Chloro-3-nitrophenyl methyl sulfone (CAS NO.97-07-4): 3-Nitro-4-chlorophenyl methyl sulfone ; EINECS 202-557-7 ; NSC 25818 ; 1-Chloro-4-(methylsulphonyl)-2-nitrobenzene ; Benzene, 1-chloro-4-(methylsulfonyl)-2-nitro- ; Sulfone, 4-chloro-3-nitrophenyl methyl (8CI)
CAS NO: 97-07-4
Product Categories: Benzene derivates 
Index of Refraction: 1.572
Molar Refractivity: 51.05 cm3
Molar Volume: 155 cm3
Surface Tension: 52.6 dyne/cm
Density: 1.52 g/cm3
Flash Point: 204.3 °C
Enthalpy of Vaporization: 64.12 kJ/mol
Boiling Point: 414.2 °C at 760 mmHg
Vapour Pressure of 4-Chloro-3-nitrophenyl methyl sulfone (CAS NO.97-07-4): 1.09E-06 mmHg at 25°C