100537-55-1 Usage
General Description
5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid is an organic compound with the molecular formula C14H10N2O3. It is a pyrazole derivative, which is a class of compounds known for their diverse biological activities. This chemical contains a furan ring, a phenyl ring, and a carboxylic acid group, all of which contribute to its properties and potential uses. 5-(2-Furyl)-1-phenyl-1H-pyrazole-3-carboxylic acid may have potential applications in medicinal chemistry and drug development due to its structural features and the potential for interacting with biological targets. Further research and studies are needed to fully understand the properties and potential uses of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 100537-55-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,5,3 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 100537-55:
(8*1)+(7*0)+(6*0)+(5*5)+(4*3)+(3*7)+(2*5)+(1*5)=81
81 % 10 = 1
So 100537-55-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H10N2O3/c17-14(18)11-9-12(13-7-4-8-19-13)16(15-11)10-5-2-1-3-6-10/h1-9H,(H,17,18)
100537-55-1Relevant articles and documents
Synthesis, nematicidal activity and docking study of novel chromone derivatives containing substituted pyrazole
Li, Wei,Li, Jiuhui,Shen, Hongfeng,Cheng, Jiagao,Li, Zhong,Xu, Xiaoyong
, p. 911 - 914 (2018)
A series of chromone derivatives containing substituted pyrazole were designed and synthesized. Preliminary bioassays showed that most of the synthesized compounds exhibited good nematicidal activity in vivo against Meloidogyne incognita at 10 mg/L. Among the tested compounds, A10 and A11 exhibited 100% inhibition rates. In addition, the molecular docking results indicated that both compound A10 and A11 interacts with amino acid residue Tyr121, Trp279, Tyr70, Trp84 and Phe330 of AChE via hydrogen bond and π–π stacking. This investigation suggested that the chromone containing substituted pyrazole scaffold could be further optimized to explore novel, high-bioactivity nematicidal leads.
