110475-31-5

• 

• Basic information

  1. Product Name: 1-Benzylpiperazine
  2. Synonyms: N-BENZYL PIPERAZINE HYDROCHLORIDE;1-BENZYLPIPERAZINE HCL;1-BENZYLPIPERAZINE HYDROCHLORIDE;1-(phenylmethyl)-piperazine monohydrochloride;4-benzylpiperazine hydrochloride;4-BENZYLPIPERAZINE HCL;N-Benzyl Piperazine Dihcl;1-Benzylpiperazine hydrochloride 97%
  3. CAS NO:110475-31-5
  4. Molecular Formula: C₁₁H₁₇N₂*Cl
  5. Molecular Weight: 212.72
  6. EINECS: 1308068-626-2
  7. Product Categories: Piperidines, Piperidones, Piperazines;Pyrans, Piperidines &Piperazines;Piperaizine;Piperazine derivates;Piperazines;Pyrans, Piperidines & Piperazines
  8. Mol File: 110475-31-5.mol
  9. Article Data: 6

• Chemical Properties

  1. Melting Point: 167-168 °C
  2. Boiling Point: 272.1 °C at 760 mmHg
  3. Flash Point: 115.6 °C
  4. Appearance: Gray power
  5. Density: 1.025 g/cm3
  6. Vapor Pressure: 0.00619mmHg at 25°C
  7. Refractive Index: N/A
  8. Storage Temp.: N/A
  9. Solubility: N/A
  10. CAS DataBase Reference: 1-Benzylpiperazine(CAS DataBase Reference)
  11. NIST Chemistry Reference: 1-Benzylpiperazine(110475-31-5)
  12. EPA Substance Registry System: 1-Benzylpiperazine(110475-31-5)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 110475-31-5(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• News
• Article

110475-31-5 Suppliers

Recommended suppliersmore

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

110475-31-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 110475-31-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,4,7 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 110475-31:
(8*1)+(7*1)+(6*0)+(5*4)+(4*7)+(3*5)+(2*3)+(1*1)=85
85 % 10 = 5
So 110475-31-5 is a valid CAS Registry Number.

InChI:InChI=1/C11H16N2.ClH/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13;/h1-5,12H,6-10H2;1H

110475-31-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name	N-Benzylpiperazine hydrochloride

1.2 Other means of identification

Product number	-
Other names	1-BENZYLPIPERAZINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:110475-31-5 SDS

110475-31-5Upstream product

• 75239-80-4 ethanol hydrochloride 
• 57260-70-5 4-benzyl-piperazine-1-carboxylic acid tert-butyl ester 
• 110-85-0 piperazine 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 142-64-3 piperazine dihydrochloride 

110475-31-5Downstream Products

• 23173-76-4 ethyl 2-(4-benzylpiperazin-1-yl)acetate 
• 123995-25-5 10-[3-(4-benzyl-piperazin-1-yl)-propyl]-10H-phenothiazine 
• 88284-64-4 2-(4-Benzyl-piperazin-1-ylmethyl)-6-morpholin-4-yl-3,4-dihydro-2H-naphthalen-1-one; hydrochloride 
• 762196-19-0 2-(4-Benzyl-piperazin-1-ylmethyl)-6-morpholin-4-yl-3,4-dihydro-2H-naphthalen-1-one 
• 47305-95-3 3-(4-Benzylpiperazino)propiophenone 
• 57260-70-5 4-benzyl-piperazine-1-carboxylic acid tert-butyl ester 
• 92042-93-8 2-(1-benzylpiperazin-4-yl)acetonitrile 

110475-31-5Related news

A comparison of 1-Benzylpiperazine (cas 110475-31-5) and methamphetamine in their acute effects on anxiety-related behavior of hooded rats08/14/2019

Following i.p. treatment with saline, 10 or 20 mg/kg 1-benzylpiperazine, or 1 or 2 mg/kg methamphetamine, hooded rats were observed in an open field, a light–dark box and (24 h after exposure to the drugs) a Y maze with one novel and one familiar arm. Both drugs increased open-field rearing and...detailed

Treatment with 1-Benzylpiperazine (cas 110475-31-5) (BZP) during adolescence of male and female hooded rats exposed to environmental enrichment: Subsequent behavioral outcomes08/13/2019

From 30 days after birth until the completion of the study, male and female rats were caged in same-sexed twos or threes either with (enriched cages, EC) or without several objects for them to explore (standard cages, SC). From 41 to 50 days of age (late adolescence), they received a daily intra...detailed

110475-31-5Relevant articles and documents

TRICYCLIC COMPOUNDS

-

Paragraph 00269, (2017/08/01)

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers or congenital diseases. Specific cancers and congenital disease includes those that are mediated by YAP/TAZ.

Synthesis and pharmacological in vitro and in vivo profile of 3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68), a selective antagonist of the neuropeptide S receptor

Okamura, Naoe,Habay, Stephen A.,Zeng, Joanne,Chamberlin, A. Richard,Reinscheid, Rainer K.

, p. 893 - 901 (2008/09/21)

Neuropeptide S (NPS) has been shown to modulate arousal, sleep wakefulness, anxiety-like behavior, and feeding after central administration of the peptide agonist to mice or rats. We report here the chemical synthesis and pharmacological characterization of SHA 66 (3-oxo-1,1-diphenyl-tetrahydro- oxazolo[3,4-a]pyrazine-7-carboxylic acid benzylamide) and SHA 68 (3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide), two closely related bicyclic piperazines with antagonistic properties at the NPS receptor (NPSR). The compounds block NPS-induced Ca2+ mobilization, and SHA 68 shows displaceable binding to NPSR in the nanomolar range. The antagonistic activity of SHA 68 seems to be specific because it does not affect signaling at 14 unrelated G protein-coupled receptors. Analysis of pharmacokinetic parameters of SHA 68 demonstrates that the compound reaches pharmacologically relevant levels in plasma and brain after i.p. administration. Furthermore, peripheral administration of SHA 68 in mice (50 mg/kg i.p.) is able to antagonize NPS-induced horizontal and vertical activity as well as stereotypic behavior. Therefore, SHA 68 could be a useful tool to characterize physiological functions and pharmacological parameters of the NPS system in vitro and in vivo. Copyright

Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

-

, (2008/06/13)

The present invention is a piperazinylalkylbenzofuran derivative of the formula wherein R1 represents a C1-4 alkyl group, R2 stands for a hydrogen atom, X means an oxygen atom, Y is a hydroxyl group, Z represents a hydrogen atom, Ar′ represents a diphenylmethyl group, a pyridyl group, a partially saturated 5-membered heterocyclic group or a phenyl group, n has a value of 0 or 1, and pharmaceutically suitable acid addition salts thereof.