142508-07-4 Usage
General Description
The chemical (1S,2R)-2-(isopropylamino)-1,2-diphenylethanol is a chiral secondary amine with a hydroxyl group and two phenyl rings. It is often used in organic synthesis and medicinal chemistry as a chiral building block for the creation of pharmaceuticals and other biologically active molecules. The isopropylamino group is a common substituent in many drugs and bioactive compounds, and the chiral nature of the molecule makes it especially useful in the creation of enantiomerically pure pharmaceuticals. (1S,2R)-2-(ISOPROPYLAMINO)-1,2-DIPHENYLETHANOL is also studied for its potential pharmacological properties, such as analgesic and anticancer effects.
Check Digit Verification of cas no
The CAS Registry Mumber 142508-07-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,5,0 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 142508-07:
(8*1)+(7*4)+(6*2)+(5*5)+(4*0)+(3*8)+(2*0)+(1*7)=104
104 % 10 = 4
So 142508-07-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H21NO/c1-13(2)18-16(14-9-5-3-6-10-14)17(19)15-11-7-4-8-12-15/h3-13,16-19H,1-2H3/t16-,17+/m1/s1
142508-07-4Relevant articles and documents
One-pot synthesis of trisubstituted 1,2-amino alcohols from deprotonated α-amino nitriles
Kison, Coralie,Opatz, Till
experimental part, p. 2740 - 2745 (2009/04/07)
A short synthesis of N,1,2-trisubstituted vicinal amino alcohols by 1,2-addition of deprotonated N-monosubstituted α-amino nitriles to aldehydes and subsequent one-pot reduction of the intermediates with borane-THF is described. This procedure leads to the predominant formation of the anti-configured products. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Facile Preparation of Some Highly Hindered Chiral 1,2-Diphenyl-2-(N-monoalkyl)amino Alcohols and N-Benzylbornamine
Jian, Li Sheng,Aiqiao, Mi,Guishu, Yang,Yaozhong, Jiang
, p. 1497 - 1503 (2007/10/02)
The preparation of some novel chiral 1,2-diphenyl-2-(N-monoalkyl)amino alcohols by a facile one-pot procedure and the synthesis of N-benzylbornamine by a reduction process are described herein.
