142851-03-4 Usage
Description
Ethyl N-Boc-piperidine-4-carboxylate is an organic compound that belongs to the class of carboxylate esters. It is a liquid with specific chemical properties that make it a valuable reagent in various chemical and pharmaceutical applications.
Uses
1. Pharmaceutical Industry:
Ethyl N-Boc-piperidine-4-carboxylate is used as a reagent for the synthesis of 3-amino-1-(5-indanyloxy)-2-propanol derivatives. These derivatives serve as sodium channel blockers, which are crucial in the treatment of stroke patients. The compound plays a significant role in modulating the activity of sodium channels, thus providing a therapeutic approach to managing stroke-related conditions.
2. Enzyme Inhibition:
Ethyl N-Boc-piperidine-4-carboxylate is also utilized as a reagent in the preparation of inhibitors for the tumour necrosis factor alpha-converting enzyme (TACE). TACE inhibitors are essential in the development of treatments for various inflammatory and autoimmune diseases, as they help regulate the production of inflammatory mediators.
3. Chemical Synthesis:
In the field of organic chemistry, Ethyl N-Boc-piperidine-4-carboxylate serves as a substrate in a palladium-catalyzed α-arylation of esters with heterocyclic bromides and chlorides. This reaction leads to the formation of 4-pyridylpiperidinyl esters, which are valuable intermediates in the synthesis of various pharmaceutical compounds and other organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 142851-03-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,8,5 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 142851-03:
(8*1)+(7*4)+(6*2)+(5*8)+(4*5)+(3*1)+(2*0)+(1*3)=114
114 % 10 = 4
So 142851-03-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H23NO4/c1-5-13(10(15)16)6-8-14(9-7-13)11(17)18-12(2,3)4/h5-9H2,1-4H3,(H,15,16)
