16156-57-3Relevant articles and documents
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Kovacewic et al.
, p. 2469,2472, 2475 (1972)
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CEREBLON BINDERS FOR THE DEGRADATION OF IKAROS
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Page/Page column 298; 299, (2019/10/23)
The present invention provides cereblon binders for the degradation of Ikaros or Aiolos by the ubiquitin proteasome pathway along with their use in therapeutic applications as described herein.
POLYCYCLIC DERIVATIVES, PREPARATION METHOD AND MEDICAL USES THEREOF
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, (2014/12/09)
Disclosed in the present invention are polycyclic derivatives as represented by general formula (I), the preparation method thereof, pharmaceutical compositions containing the derivatives and uses thereof as therapeutical agents, especially the GPR40 agonist and in preparation of drugs for treating diseases like diabetes and metabolic disorders, etc., wherein each substituent in the general formula (I) has the same definition as in the description.