185428-55-1Relevant articles and documents
Visible-Light-Mediated Nitration of Protected Anilines
Düsel, Simon J. S.,K?nig, Burkhard
, p. 2802 - 2807 (2018/03/09)
The photocatalytic nitration of protected anilines proceeds with riboflavin tetraacetate as an organic photoredox catalyst. Sodium nitrite serves as the NO2 source in this visible-light-driven room temperature reaction. Various nitroanilines are obtained in moderate to good yields without the addition of acid or stoichiometric oxidation agents. The catalytic cycle is closed by aerial oxygen as the terminal oxidant.
Intermediates for the synthesis of benzimidazole derivatives and a process for the preparation thereof
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, (2008/06/13)
This invention provides a process for the preparation of a benzimidazole derivative (I) or a pharmaceutically acceptable salt thereof, 1wherein R1 is C1-C6 alkyl, C1-C6 alkoxyl, etc., R2 is C1-C6 alkyl, and R3 is hydrogen or a protecting group, which exhibits excellent hyopoglycemic action, said process comprising condensation of an amine derivative (III) with a carboxylic acid derivatives (II) to afford a compound (IV), followed by cyclization of compound (IV) in the presence of an acid.
Process for producing N-acylnitroaniline derivative
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Page 8, (2010/01/31)
A process of reacting a nitroaniline compound of formula (2); with acid anhydride or acid chloride is carried out in the presence of an alkali metal compound or an alkaline earth metal compound to produce acylnitroaniline derivative. The process further includes the step of reacting the resulting product with a compound of formula (5);R2-Y to produce an N-acylnitroaniline derivative of formula (1);
