188577-68-6 Usage
Description
2-Amino-4,5-dichloropyridine is a chemical compound with the molecular formula C5H4Cl2N2. It is a derivative of pyridine, featuring a six-membered ring with five carbon atoms and one nitrogen atom, distinguished by the presence of two chlorine atoms and one amino group attached to the pyridine ring. 2-Amino-4,5-dichloropyridine is recognized for its chemical properties and reactivity, making it a valuable building block in organic synthesis and a significant intermediate in the production of pharmaceuticals and agrochemicals.
Uses
Used in Pharmaceutical Industry:
2-Amino-4,5-dichloropyridine is used as a key intermediate for the synthesis of various drugs. Its unique structure and reactivity allow for the development of new compounds with therapeutic potential, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Amino-4,5-dichloropyridine is utilized as a crucial component in the production of pesticides. Its chemical properties enable the creation of effective compounds for pest control, thereby supporting agricultural productivity and crop protection.
Used in Organic Synthesis:
2-Amino-4,5-dichloropyridine is employed as a versatile building block in organic synthesis. Its ability to participate in various chemical reactions facilitates the creation of a wide range of compounds with diverse applications across different industries.
Used in Biological and Pharmacological Research:
2-Amino-4,5-dichloropyridine is studied for its potential biological and pharmacological activities. Its exploration as a compound with therapeutic potential is significant for discovering new treatments and advancing our understanding of its interactions with biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 188577-68-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,5,7 and 7 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 188577-68:
(8*1)+(7*8)+(6*8)+(5*5)+(4*7)+(3*7)+(2*6)+(1*8)=206
206 % 10 = 6
So 188577-68-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H4Cl2N2/c6-3-1-5(8)9-2-4(3)7/h1-2H,(H2,8,9)
188577-68-6Relevant articles and documents
Identification of azabenzimidazoles as potent JAK1 selective inhibitors
Vasbinder, Melissa M.,Alimzhanov, Marat,Augustin, Martin,Bebernitz, Geraldine,Bell, Kirsten,Chuaqui, Claudio,Deegan, Tracy,Ferguson, Andrew D.,Goodwin, Kelly,Huszar, Dennis,Kawatkar, Aarti,Kawatkar, Sameer,Read, Jon,Shi, Jie,Steinbacher, Stefan,Steuber, Holger,Su, Qibin,Toader, Dorin,Wang, Haixia,Woessner, Richard,Wu, Allan,Ye, Minwei,Zinda, Michael
, p. 60 - 67 (2016)
We have identified a class of azabenzimidazoles as potent and selective JAK1 inhibitors. Investigations into the SAR are presented along with the structural features required to achieve selectivity for JAK1 versus other JAK family members. An example from
IMPROVED METHODS, KITS, COMPOSITIONS AND DOSING REGIMENS FOR THE USE OF HETEROCYCLIC INHIBITORS OF ERK1 AND ERK2
-
Page/Page column 132-134, (2021/05/07)
The present application provides improved compositions, methods, kits and dosing regimens for the use of heterocyclic compounds and pharmaceutically acceptable salts, prodrugs, solvates, hydrates, or stereoisomers thereof. These compositions, methods, kit
HETEROCYCLIC INHIBITORS OF ERK1 AND ERK2 AND THEIR USE IN THE TREATMENT OF CANCER
-
Paragraph 0558-0559, (2017/01/02)
The present application provides novel heterocyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful for inhibiting ERK1/2. By administering to a patient in need a
