188577-71-1

Basic information

• Product Name: N-(4,5-DICHLOROPYRID-2-YL)-PIVALOYLAMIDE
• Synonyms: N-(4,5-DICHLOROPYRID-2-YL)-PIVALOYLAMIDE
• CAS NO: 188577-71-1
• Molecular Formula: C10H12Cl2N2O
• Molecular Weight: 247.12
• Mol File: 188577-71-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4,5-DICHLOROPYRID-2-YL)-PIVALOYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4,5-DICHLOROPYRID-2-YL)-PIVALOYLAMIDE(188577-71-1)
• EPA Substance Registry System: N-(4,5-DICHLOROPYRID-2-YL)-PIVALOYLAMIDE(188577-71-1)

Safety Data

• Hazardous Substances Data: 188577-71-1(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 19798-80-2 2-Amino-4-chloropyridine 
• 188577-70-0 4-chloro-2-trimethylacetamidopyridine 

Downstream Products

• 188577-68-6 4,5-dichloro-2-aminopyridine 
• 1446244-52-5 N-(3-((2-amino-5-chloro-3-nitropyridin-4-yl)oxy)phenyl)acrylamide 
• 1446244-53-6 N-(3-((2,3-diamino-5-chloropyridin-4-yl)oxy)phenyl)acrylamide 
• 1446244-32-1 N-(3-(6-chloro-2-(4-(4-methylpiperazin-1-yl)phenyl)-3H-imidazo[4,5-b]pyridin-7-yloxy)phenyl)acrylamide 
• 662116-66-7 2,3-diamino-4,5-dichloropyridine 
• 662116-67-8 4,5-dichloro-3-nitropyridin-2-ylamine 

Relevant articles and documents

HETEROCYCLIC INHIBITORS OF ERK1 AND ERK2 AND THEIR USE IN THE TREATMENT OF CANCER

The present application provides novel heterocyclic compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful for inhibiting ERK1/2. By administering to a patient in need a

NOVEL IMIDAZOPYRIDINE DERIVATIVES AS A TYROSINE KINASE INHIBITOR

Provided is a novel imidazopyridine derivative having irreversible tyrosine kinase inhibiting activities, and a pharmaceutical composition comprising the same which can be useful for prevention or treatment of inflammatory diseases, autoimmune diseases, p

PYRAZIN-2-YL-PYRIDIN-2-YL-AMINE AND PYRAZIN-2-YL-PYRIMIDIN-4-YL-AMINE COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain biarylamine compounds (referred to herein as BAA compounds), and especially certain pyrazin- 2 - yl -pyridin- 2 -yl -amine and pyrazine - 2 - yl -pyrimidin- 4 - yl -amine compounds of formula (I), which, inter alia, inhibit Checkpoint Kinase 1 (CHK1 ) kinase function The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1. that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc., optionally in combination with another agent, for example, (a) a DNA topoisomerase I or Il inhibitor; (b) a DNA damaging agent; (c) an antimetabolite or TS inhibitor; (d) a microtubule targeted agent; and (e) ionisiπq radiation. wherein: -X= is independently -CRA5= or -N=; and the rest of the substituents are as specified in the claims.