190273-89-3Relevant articles and documents
Microwave-assisted preparation of fused bicyclic heteroaryl boronates: Application in one-pot suzuki couplings
DiMauro, Erin F.,Vitullo, Jason R.
, p. 3959 - 3962 (2006)
The rapid and efficient synthesis of various disubstituted 5,6-fused heterocycles using a microwave-assisted one-pot cyclization-Suzuki coupling approach is described. This work highlights the tolerance of the boronic ester functional group to a variety o
TREATMENT OF FIBROSIS WITH IRE1 SMALL MOLECULE INHIBITORS
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Paragraph 00195, (2020/11/30)
Provided herein are methods of using IRE1 small molecule inhibitors in combination therapies for treating fibrosis in a subject. The IRE1 small molecule inhibitors described herein may be used in combination therapies for treating fibrosis
IRE1 SMALL MOLECULE INHIBITORS
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Paragraph 00255, (2019/05/30)
Provided herein are small molecule inhibitors for the targeting or IRE1 protein family members. Binding may be direct or indirect. Further provided herein are methods of using IRE1 small molecule inhibitors for use in treating or ameliorating cancer in a subject. Moreover, IRE1 small molecule inhibitors described herein are for the treatment of cancer, where the cancer is a solid or hematologic cancer.