1000-62-0

Basic information

• Product Name: 1-Ethoxy-2-(trimethylsilyl)ethyne
• Synonyms: (Ethoxyethynyl)trimethylsilane;1-(Trimethylsilyl)-2-ethoxyacetylene;1-Ethoxy-2-(trimethylsilyl)ethyne;Ethoxy(trimethylsilyl)acetylene
• CAS NO: 1000-62-0
• Molecular Formula: C₇H₁₄OSi
• Molecular Weight: 142.27
• Mol File: 1000-62-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 57.2 °C(Press: 34 Torr)
• Appearance: /
• Density: 0.8276 g/cm3
• Solubility: insol H2O; freely sol most common solvents.
• CAS DataBase Reference: 1-Ethoxy-2-(trimethylsilyl)ethyne(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Ethoxy-2-(trimethylsilyl)ethyne(1000-62-0)
• EPA Substance Registry System: 1-Ethoxy-2-(trimethylsilyl)ethyne(1000-62-0)

Safety Data

• Hazardous Substances Data: 1000-62-0(Hazardous Substances Data)

Usage

Physical properties

bp 57 °C/34 mmHg; d 0.828 g cm?3.

Uses

Ethoxy(trimethylsilyl)acetylene is usually used as mild agent for conversion of carboxylic acids into carboxylic anhydrides;dehydrative condensation agent for carboxylic acids and amines and alcohols; trimethylsilylketene precursor;2π component in cycloaddition reactions.

Upstream product

• 2857-97-8 trimethylsilyl bromide 
• 927-80-0 1-ethoxyacetylene 
• 75-77-4 chloro-trimethyl-silane 
• 621-62-5 chloroacetaldehyde diethyl acetal 

Downstream Products

• 960502-78-7 3-ethoxy-4-(4-methoxyphenyl)-2-trimethylsilylcyclopent-2-enone 
• 960502-77-6 3-ethoxy-2-trimethylsilyl-4-phenylcyclopent-2-enone 
• 185200-20-8 [Rh(C₄H₇N₂O₂)2(PPh₃)(cis-CHCHOEt)] 
• 91634-02-5 5-ethoxy-1-phenyl-1H-[1,2,3]triazole 
• 4071-91-4 N-Phenyl-2-trimethylsilanyl-acetamide 
• 2916-76-9 methyl (trimethylsilyl)acetate 
• 7318-74-3 (dimethylamino)dimethoxy borane 
• 23184-28-3 N,N-dimethyl(trimethylsilyl)acetamide 
• 129164-55-2 2-ethoxy-6-p-tolyl-3-(trimethylsilyl)-4H-pyran-4-one 
• 65384-67-0 4-hydroxy-3-(4-methylbenzoyl)-6-(4-methylphenyl)-2H-pyran-2-one 
• 14895-21-7 3-benzoyl-4-hydroxy-6-phenyl-2H-pyran-2-one 
• 129164-54-1 2-ethoxy-6-phenyl-3-(trimethylsilyl)-4H-pyran-4-one 
• 4071-88-9 trimethylsilanyl-acetic acid ethyl ester 
• 58160-83-1 (Z)-3-Phenyl-2-trimethylsilanyl-acrylic acid ethyl ester 

Relevant articles and documents

A MILD AND FACILE SYNTHESIS OF CARBOXYLIC ANHYDRIDES

Reaction of carboxylic acids with trimethylsilylethoxyacetylene in an inert solvent under mild conditions affords the corresponding carboxylic anhydrides in almost quantitative yields.

Linear, Mannitol-Based Poly(anhydride-esters) with High Ibuprofen Loading and Anti-Inflammatory Activity

Sugar alcohols, such as mannitol and xylitol, are biocompatible polyols that have been used to make highly cross-linked polyester elastomers and dendrimers for tissue engineering and drug delivery. However, research that utilizes the secondary hydroxyl gr

Ynol Ethers as Ketene Equivalents in Rhodium-Catalyzed Intermolecular [5 + 2] Cycloaddition Reactions

The previously unexplored metal-catalyzed [5 + 2] cycloadditions of vinylcyclopropanes (VCPs) and electron-rich alkynes (ynol ethers) have been found to provide a highly efficient, direct route to dioxygenated seven-membered rings, a common feature of num