65384-67-0

Upstream product

• 2085-31-6 2-diazo-1,3-diphenylpropane-1,3-dione 
• 55991-68-9 5-(p-tolyl)-2,3-dihydro-2,3-furandione 
• 624-31-7 4-tolyl iodide 
• 2227-58-9 3-(4-methylphenyl)prop-2-ynoic acid 
• 1000-62-0 trimethylsilylethoxyacetylene 
• 926-65-8 vinyl isopropyl ether 

Downstream Products

• 145489-54-9 3-<2-amino-4,5-dimethylphenylimino(p-toluoyl)>-4-hydroxy-6-(p-tolyl)-2H-pyran-2-one 
• 145489-53-8 3-<2-amino-4,5-dichlorophenylimino(p-toluoyl)>-4-hydroxy-6-(p-tolyl)-2H-pyran-2-one 
• 18357-35-2 2,6-bis(4-methylphenyl)-4H-pyran-4-one 
• 84261-25-6 5-bromo-4-hydroxy-3-(p-toluoyl)-6-(p-tolyl)-2H-pyran-2-one 
• 145489-60-7 3-<2-acetylaminophenylimino(p-toluoyl)>-4-hydroxy-6-(p-tolyl)-2H-pyran-2-one 
• 145489-52-7 3-<2-aminophenylimino(p-toluoyl)>-4-hydroxy-6-(p-tolyl)-2H-pyran-2-one 
• 145489-51-6 4-hydroxy-3--6-(p-tolyl)-2H-pyran-2-one 

Relevant academic research and scientific papers

Gold-catalyzed homo- And cross-annulation of alkynyl carboxylic acids: a facile access to substituted 4-hydroxy 2: H -pyrones and total synthesis of pseudopyronine A

A Au(i)-catalyzed homo- and cross-annulation reaction of alkynyl carboxylic acids offering 3,6-disubstituted 4-hydroxy 2H-pyrones has been demonstrated. The reaction tolerates various substituted alkynyl carboxylic acids and moderate to good yields of α-pyrone scaffolds have been observed. Later, a gram-scale reaction of the acid and the total synthesis of the natural product pseudopyronine A have been carried out successfully.

Functionalization of the Methyl C(sp 3)–H Bond of 2,3-Dimethylquinoxaline with 5-Arylfuran-2,3-diones

Abstract: 5-Arylfuran-2,3-diones reacted with 2,3-dimethylquinoxaline to give mono- andbis-C-acylation products, (2Z,4Z)-1-aryl-3,4-dihydroxy-5-(3-methylquinoxalin-2-yl)penta-2,4-dien-1-onesand (2Z,2′Z,4Z,4′Z)-5,5′-(quinoxaline-2,3-diyl)bis[(2Z,4Z)-1-aryl

Investigation of the interaction of 5-aryl-2,3-dihydro-2,3-furandiones with compounds containing C=N and C≡N bonds simultaneously

Aroylketenes, generated by the thermolysis of 5-aryl-2,3-dihydro-2,3- furandiones, react with S-methyl-N-cyano-N′-phenylisothiourea, N-cyano-N′,N′-dimethylformamidine, and N,N-bis(β-cyanoethyl) cyanamide with the formation of 6-aryl-2-[(methylthio)(phenyl

Synthesis of Pyranones by Dimerization of Aroylketenes

Thermolysis of 5-aryl-2,3-dihydrofuran-2,3-diones in the presence of dibenzoyldiazomethane yields 6-aryl-3-aroyl-4-hydroxy-2H-pyran-2-ones and 3-aroyl-4-hydroxy-5,6-diphenyl-2H-pyran-2-ones, as the result of [2+4] cycloaddition of aroylketenes that arise from thermolysis both of the furandiones and of dibenzoyldiazomethane. Thermolysis of 5-aryl-4-methyl-2,3-dihydrofuran-2,3-diones and dibenzoyldiazomethane results in exclusive formation of 6-aryl-3-aroyl-3,5-dimethyl-3,4-dihydro-2H-pyran-2,4-diones.