1000175-92-7Relevant academic research and scientific papers
Tuning Regioselectivity of Wacker Oxidation in One Catalytic System: Small Change Makes Big Step
Hu, Kang-Fei,Ning, Xiao-Shan,Qu, Jian-Ping,Kang, Yan-Biao
, p. 11327 - 11332 (2018)
A regioselectivity switchable aerobic Wacker-Tsuji oxidation has been developed using catalytic tert-butyl nitrite as a simple organic redox cocatalyst. By solely switching the solvent, either substituted aldehydes or ketones could be prepared under mild
Tert-Butyl Nitrite: Organic Redox Cocatalyst for Aerobic Aldehyde-Selective Wacker-Tsuji Oxidation
Ning, Xiao-Shan,Wang, Mei-Mei,Yao, Chuan-Zhi,Chen, Xian-Min,Kang, Yan-Biao
, p. 2700 - 2703 (2016/06/15)
An aldehyde-selective aerobic Wacker-Tsuji oxidation is developed. Using tert-butyl nitrite as a simple organic redox cocatalyst instead of copper or silver salts, a variety of aldehydes were achieved as major products in up to 30/1 regioselectivity as well as good to high yields at room temperature.
Mixed phosphane η5-CpRuCl(PR3)2 complexes as ambifunctional catalysts for anti-markovnikov hydration of terminal alkynes
Boeck, Florian,Kribber, Thomas,Xiao, Li,Hintermann, Lukas
supporting information; experimental part, p. 8138 - 8141 (2011/07/08)
The catalytic activity of [CpRu(L)2(MeCN)]PF6 (L = 2-diphenylphosphinopyridine with bulky groups at C-6) for anti-Markovnikov hydration of terminal alkynes to aldehydes is retained when one heterocyclic ligand L is replaced by L′ = PPh3. Equal amounts of CpRuCl(PPh3)2 (1) and phosphane L in acetone solution equilibrate to a mixture of 1, CpRuCl(L)(PPh3) (2), and CpRuCl(L)2 (3), which acts as highly active in situ catalyst for preparative anti-Markovnikov hydration of alkynes in water-rich media (2 mol % [Ru], 60 °C, 3-18 h in 4:1 (v/v) acetone/water). Reactions were completed in 15 min at 160 °C.
Iterative synthesis of oligo-1,4-diols via catalytic anti-Markovnikov hydration of terminal alkynes
Kribber, Thomas,Labonne, Aurelie,Hintermann, Lukas
, p. 2809 - 2818 (2008/03/14)
A sequential, iterative synthesis of oligo-1,4-diol building blocks has been realized via (a) propargylation of an aldehyde with allenylzinc bromide, (b) alcohol protection and (c) ruthenium-catalyzed anti-Markovnikov hydration of the terminal alkyne to r
