1001906-63-3

Usage

Uses

Used in Pharmaceutical Industry:
1-(1H-Indazol-5-yl)ethanone is used as a key intermediate in the synthesis of various pharmaceutical substances. Its indazole nucleus provides a useful pharmacophoric group that can be exploited in the development of new drugs, making it a valuable compound in medicinal chemistry.
Used in Chemical Research:
1-(1H-Indazol-5-yl)ethanone is used as a research compound in the field of organic chemistry. It serves as a model for studying the properties and reactions of indazole-containing compounds, contributing to the understanding of their potential applications in various chemical processes.
Used in Organic Synthesis:
1-(1H-Indazol-5-yl)ethanone is used as a building block in the synthesis of complex organic molecules. Its unique structure allows for the creation of a wide range of chemical products, making it a versatile compound in the field of organic synthesis.

Upstream product

• 877264-73-8 tert-butyl 5-acetyl-1H-indazole-1-carboxylate 
• 1173003-55-8 1-(1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-5-yl)ethanone 
• 1093306-90-1 N-methoxy-N-methyl-1H-indazole-5-carboxamide 
• 676-58-4 methylmagnesium chloride 
• 61700-61-6 1H-indazole-5-carboxylic acid 

Downstream Products

• 1093302-85-2 4-(1H-indazol-5-yl)-N-phenyl-1,3-thiazol-2-amine 
• 1093302-88-5 N-benzyl-4-(1H-indazol-5-yl)-1,3-thiazol-2-amine 
• 1093302-90-9 4-(1H-indazol-5-yl)-N-(2-phenylethyl)-1,3-thiazol-2-amine 
• 877264-73-8 tert-butyl 5-acetyl-1H-indazole-1-carboxylate 

Relevant academic research and scientific papers

Scaffold oriented synthesis. Part 4: Design, synthesis and biological evaluation of novel 5-substituted indazoles as potent and selective kinase inhibitors employing heterocycle forming and multicomponent reactions

We report the synthesis and biological evaluation of 5-substituted indazoles as kinase inhibitors. The compounds were synthesized in a parallel synthesis fashion from readily available starting materials employing heterocycle forming and multicomponent reactions and were evaluated against a panel of kinase assays. Potent inhibitors were identified for Gsk3β, Rock2, and Egfr.

AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME

Compounds are disclosed that have a formula represented by the following: (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including

SUBSTITUTED N-BICYCLICALKYL BICYCLIC CARBOXYAMIDE COMPOUNDS

This invention provides a compound of the formula (I): And their use for the treatment of disease conditions caused by overactivation of the VR1 receptor such as pain, or the like in mammal. This invention also provides a pharmaceutical composition compri