100227-05-2Relevant articles and documents
The in Vitro Dental Plaque Inhibitory Properties of a Series of N-alkylamines
Wentland, Mark P.,Bailey, Denis M.,Powles, Ronald G.,Slee, , Andrew M.,Sedlock, David M.
, p. 2024 - 2027 (1988)
A series of novel N-alkylamine hydrohalides has been prepared and evaluated as inhibitors of dental plaque formation, in vitro.Several members of the series exhibited potency ca. 9-fold greater than that of chlorhexidine vs S
Antimicrobial (N-1-octyl-4(1H)-pyridinylidine)octanamine and acid addition salts thereof and methods of use and compositions thereof
-
, (2008/06/13)
N-[1-(alkyl or arylmethyl)-4(1H)-pyridinylidine]-alkanamine and pharmaceutically acceptable acid addition salts thereof, for example, N-(1-octyl-4(1H)-pyridinylidine)octanamine monohydrochloride salt, which are useful as antimicrobial agents, especially on living tissues and nonliving surfaces and most especially against pathogenic dental microbes, and a process for preparation, methods of use and compositions thereof are disclosed.