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10030-78-1

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10030-78-1 Usage

Description

6-HYDROXY-2-METHYLAMINOPURINE, also known as 6-Methylaminopurine-9-hydroxide, is a purine derivative that serves as a non-specific protein kinase inhibitor in biochemical research. As an analog of adenine, it functions as a competitive inhibitor for various kinases, such as cyclic AMP-dependent protein kinases and protein kinase C. 6-HYDROXY-2-METHYLAMINOPURINE has demonstrated the ability to inhibit the proliferation of leukemia and breast cancer cells, positioning it as a potential anti-cancer agent. Furthermore, it has been studied for its potential to stimulate plant growth and development due to its role as a cytokinin, a class of plant hormones that regulate cell division and differentiation.

Uses

Used in Biochemical Research:
6-HYDROXY-2-METHYLAMINOPURINE is used as a non-specific protein kinase inhibitor for studying the effects of kinase activity on various biological processes. Its ability to competitively inhibit multiple kinases makes it a valuable tool in understanding the roles of these enzymes in cellular functions.
Used in Pharmaceutical Development:
6-HYDROXY-2-METHYLAMINOPURINE is used as a potential anti-cancer agent, particularly for targeting the proliferation of leukemia and breast cancer cells. Its inhibitory effects on cancer cell growth make it a candidate for further development in oncology.
Used in Plant Biology Research:
6-HYDROXY-2-METHYLAMINOPURINE is used as a cytokinin in plant growth and development studies. Its role in regulating cell division and differentiation allows researchers to explore its potential applications in agriculture and horticulture for enhancing plant productivity and improving crop quality.

Check Digit Verification of cas no

The CAS Registry Mumber 10030-78-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,3 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10030-78:
(7*1)+(6*0)+(5*0)+(4*3)+(3*0)+(2*7)+(1*8)=41
41 % 10 = 1
So 10030-78-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H7N5O/c1-7-6-10-4-3(5(12)11-6)8-2-9-4/h2-3H,1H3,(H2,7,8,9,10,11,12)

10030-78-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(methylamino)-3,7-dihydropurin-6-one

1.2 Other means of identification

Product number -
Other names N2-Methylguanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10030-78-1 SDS

10030-78-1Relevant articles and documents

A Convenient Synthesis of N2-Alkylated Guanines

Zhu,Qin,Liu,Luo

, p. 874 - 878 (2019)

An improved three-step synthesis of N2-alkylated guanines has been developed starting from N2-Boc-protected 2-amino-6-chloropurine which was treated with Boc2O, and the resulting doubly N2,9-protected derivative was subjected to N2-alkylation with alkyl halides, followed by hydrolysis. The advantages of this procedure include short reaction steps, simple operations, and good yields.

Synthesis of N2-alkyl(aryl, dialkyl, cycloalkyl)guanines

Kochergin,Persanova,Aleksandrova,Gutorov,Korsunskii

, p. 338 - 341 (2007/10/03)

Novel N2-alkyl(aryl, dialkyl, cycloalkyl)guanines have been synthesized by treating 2-chloro-7-benzylhypoxanthine with amines and debenzylation of the N2-substituted 7-benzylguanine products by means of palladium catalyzed hydrogenat

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