5446-89-9

Basic information

• Product Name: 2-(methylsulfanyl)-3,5-dihydro-6H-purin-6-one
• CAS NO: 5446-89-9
• Molecular Formula: C₆H₆N₄OS
• Molecular Weight: 182.203
• Mol File: 5446-89-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 313.5°C at 760 mmHg
• Flash Point: 143.4°C
• Density: 1.78g/cm³
• Vapor Pressure: 0.000494mmHg at 25°C
• Refractive Index: 1.857
• CAS DataBase Reference: 2-(methylsulfanyl)-3,5-dihydro-6H-purin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(methylsulfanyl)-3,5-dihydro-6H-purin-6-one(5446-89-9)
• EPA Substance Registry System: 2-(methylsulfanyl)-3,5-dihydro-6H-purin-6-one(5446-89-9)

Safety Data

• Hazardous Substances Data: 5446-89-9(Hazardous Substances Data)

Usage

Synonyms

6-thioxanthine

Molecular structure

Closely related to caffeine and theobromine

Classification

Purine derivative and xanthine analog

Function

Inhibitor of xanthine oxidase

Enzyme target

Xanthine oxidase, involved in purine metabolism

Applications

a. Study of purine metabolism
b. Research tool for developing xanthine oxidase inhibitors

Potential treatments

Gout and hyperuricemia

Additional investigations

Anti-cancer and anti-inflammatory properties

Relevance

Pharmaceutical research and drug development

Upstream product

• 54030-57-8 5,6-diamino-2-(methylthio)pyrimidin-4(3H)-one 
• 122-51-0 orthoformic acid triethyl ester 
• 2487-40-3 2,3-dihydro-2-thioxo-9H-purine-6(1H)-one 
• 77-78-1 dimethyl sulfate 
• 130890-47-0 5-(N'-Ethoxycarbonylthiocarbamoyl)amino-4-ethoxycarbonylimidazole 
• 54030-57-8 5,6-diamino-4-hydroxy-2-(methylsulfanyl)pyrimidine 
• 64194-62-3 4-amino-5-formamido-6-hydroxy-2-mercaptopyrimidine 
• 2487-40-3 6-hydroxy-2-mercaptopurine 
• 2487-40-3 2-thioxanthine 
• 64-18-6 formic acid 
• 1074-41-5 6-amino-2-methylsulfanylpyrimidin-4(3H)-one 

Downstream Products

• 142581-06-4 2-(4-chloro-anilino)-1,7-dihydro-purin-6-one 
• 19545-00-7 N²-Ethylguanine 
• 1445-15-4 2-(dimethylamino)-1,7-dihydro-6H-purin-6-one 
• 40769-49-1 2-anilino-1,7-dihydro-purin-6-one 
• 10030-78-1 1,7-dihydro-2-(methylamino)-6H-purin-6-one 
• 22529-10-8 2-methylamino-1,7-dihydro-purine-6-thione 
• 66191-23-9 2-methylthio-6-chloropurine 
• 6969-28-4 2-hydrazino-1,7-dihydro-purin-6-one 
• 41286-86-6 2-methanesulfonyl-1,7-dihydro-purin-6-one 
• 66191-23-9 2-methylthio-N-6-chloropurine 
• 1096435-29-8 2-methylthio-6-anilinopurine 
• 1681-11-4 dimethyl-(2-methylsulfanyl-7⁽⁹⁾H-purin-6-yl)-amine 

Relevant articles and documents

SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS

The invention relates to substituted 6-anilino-9-heterocyclylpurine derivatives of formula (I) wherein R denotes one to five substituents independently selected from the group comprising hydrogen, halogen, hydroxy, amino, alkyloxy and alkyl group, R2 is s

Substituted 6-(Benzylamino) Purine Riboside Derivatives, Use Thereof and Compositions Containing These Derivatives

The invention relates to 2-substituted-6-(substituted benzylamino)purine riboside derivatives of the general formula I. These compounds possess antiapoptotic, anti-inflammatory and differentiating activities. The invention relates also to the compositions, which contain these derivatives as active ingredients.

SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES

The invention relates to substituted 6-anilinopurine derivatives of the general formula I, wherein R denotes one to five substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino, alkyloxy and alkyl group, and R2 denotes amino, halogen, nitro, thio, alkylthio or alkyl group for use as inhibitors of cytokinin oxidase/dehydrogenase. The invention also relates to the compositions containing these derivatives.