100331-46-2

Upstream product

• 350-03-8 methyl-3-pyridylketone 
• 151-50-8 potassium cyanide 
• 62-53-3 aniline 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 230638-06-9 5-benzyl-4-hydroxy-1-phenyl-1H-[2,3']bipyridinyl-6-one 
• 230638-05-8 4-hydroxy-1,5-diphenyl-1H-[2,3']bipyridinyl-6-one 
• 230638-01-4 5-ethyl-4-hydroxy-1-phenyl-1H-[2,3']bipyridinyl-6-one 

Relevant academic research and scientific papers

Chiral Cadmium(II) Metal-Organic Framework from an Achiral Ligand by Spontaneous Resolution: An Efficient Heterogeneous Catalyst for the Strecker Reaction of Ketones

A thermally stable cadmium-based chiral metal-organic framework (MOF), {[Cd2(L)(H2O)(DMF)]·3DMF·2H2O}n (1; DMF = N,N-dimethylformamide), has been synthesized from an achiral ligand by spontaneous resolution. The MOF features 1D open channels with a large density of active metal sites and has a 3,6-c binodal net with a rare sit 3,6-conn topology. The metal-bound water and DMF solvents could be easily removed along with the guest molecules in the lattice upon activation to afford the desolvated framework 1′. It exhibits microporous nature, as confirmed by the gas-sorption measurements with carbon dioxide uptake of 43.2 cm3 g-1 at 273 K. The open metal sites in the framework make it an outstanding heterogeneous catalyst in the Strecker reaction for the synthesis of α-aminonitriles in a solvent-free state at room temperature with excellent conversion yields.

A microporous metal-organic framework catalyst for solvent-free strecker reaction and CO2 fixation at ambient conditions

The self-assembly of zinc(II) acetate tetrahydrate, a flexible tetrapyridyl ligand, tetrakis(3-pyridyloxymethylene)methane (3-tpom), a bent dicarboxylic acid, and 4,4′-(dimethylsilanediyl)bis- benzoic acid (H2L) under solvothermal conditions ha

Design and Construction of a Chiral Cd(II)-MOF from Achiral Precursors: Synthesis, Crystal Structure and Catalytic Activity toward C-C and C-N Bond Forming Reactions

Using achiral components, a V-shaped dicarboxylic acid (H2L) and a conformationally flexible bidentate linker (bpp), a thermally stable chiral metal organic framework {[Cd(bpp)(L)(H2O)]·DMF}n (1), where H2L = 4,

Sulfated tungstate: A green catalyst for Strecker reaction

A straightforward, mild, efficient, and general method has been developed for the synthesis of α-aminonitriles via Strecker reaction starting from aldehydes or ketones, amines, and trimethylsilyl cyanide in the presence of sulfated tungstate as a heterogeneous mild solid acid catalyst at room temperature and solvent free condition. The developed method has been successfully applied for the synthesis of a wide range of α-aminonitriles with variable functionality.

Organometallic hollow spheres bearing bis(N-Heterocyclic carbene)-palladium species: Catalytic application in three-component Strecker reactions

Hollow-sphere catalysts were prepared by means of 3D network formation between a tetraimidazolium building block and palladium acetate. The bis(N-heterocyclic carbene)-palladium species that were concomitantly formed during growth of the hollow spheres sh

N-HETEROCYCLIC CARBENE-AMIDO PALLADIUM(II) CATALYSTS AND METHOD OF USE THEREOF

A new N-heterocyclic catalyst system which contains N-heterocyclic carbene and amido as ligands, which are strongly bound to a palladium metal. Another heteroatom functionality can be used as a third ligand L. The NHC-amidate ligand system is unique in structure, and shows excellent reactivities in a number of chemical reactions. The chemical reactions include carbon-carbon and carbon-heteroatom (oxygen and nitrogen) bond formations, and oxidation reactions of saturated carbon chemicals via C—H activation.

Synthesis and reactions of 4-hydroxy-2(1H)-pyridones with thienyl and pyridyl substituents in position 6 starting with azomethines and malonates

The reaction of 4 with substituted diethyl malonates 5a, or 'magic malonates' (bis-2,4,6-trichlorophenylmalonates 5b) leads to 4-hydroxy-2(1H)- pyridones 6. The azomethines 4 are prepared via the Strecker compounds 3 starting with methyl ketones 1, anilines, and potassium cyanide. Chlorination of pyridones 6 with sulfuryl chloride leads to compounds 7 while nitration gives 9.

Derivatives of 2-(3-pyridyl)-2-phenylaminoacetic acid and their use as antifungals in the field of argriculture

New derivatives of 2-(3-pyridyl)-2-phenylaminoacetic acid, of the formula: STR1 with: R0 : --CN, --COOH, CONH2, COOR4, R1 : H, lower alkyl, cycloalkyl, phenyl, if appropriate substituted, aralkyl if appropriate substituted, R2 : H, lower alkyl, if appropriate substituted, Ar: phenyl if appropriate substituted, Z: halogen, lower alkyl, lower alkoxy, lower alkylthio. They can be employed in agriculture for combating phytopathogenic fungi such as the sclerotiniaceae.