100448-58-6 Usage
Functional group
Hydrazone derivative
The compound contains a functional group with the general structure R1R2C=NNH2, which is characteristic of hydrazone derivatives.
Class of compound
Organic
As it is composed of carbon-based molecules, 2-(aminocarbonyl)-4-chloro-5-aminobenzaldehyde hydrazone is classified as an organic compound.
Usage
Chemical research and pharmaceutical development
2-(aminocarbonyl)-4-chloro-5-aminobenzaldehyde hydrazone is utilized in chemical research and pharmaceutical development due to its unique structure and properties.
Potential applications
Medicine
The compound may have potential applications in the field of medicine, although further research is needed to explore its specific uses.
Further exploration
Scientific research
The properties and potential uses of 2-(aminocarbonyl)-4-chloro-5-aminobenzaldehyde hydrazone can be further investigated through scientific research to better understand its capabilities and limitations.
Check Digit Verification of cas no
The CAS Registry Mumber 100448-58-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,4 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 100448-58:
(8*1)+(7*0)+(6*0)+(5*4)+(4*4)+(3*8)+(2*5)+(1*8)=86
86 % 10 = 6
So 100448-58-6 is a valid CAS Registry Number.
100448-58-6Relevant academic research and scientific papers
Synthesis, Saludiuretic, and Antihypertensive Activity of 6,7-Disubstituted 1(2H)- and 3,4-Dihydro-1(2H)-phthalazinones
Cherkez, S.,Herzig, J.,Yellin, H.
, p. 947 - 959 (2007/10/02)
The synthesis of the isomeric series 6-chloro-7-sulfamoyl-and 7-chloro-6-sulfamoyl-1(2H)-phthalazinones (1 and 2) and 6-chloro-7-sulfamoyl- and 7-chloro-6-sulfamoyl-3,4-dihydro-1(2H)-phthalazinones (3 and 4), combining structural features characteristic to furosemide and hydralazine, is described, the mechanism of the formation of 1 and 2 is discussed, and their structure-activities relationships are studied.Preliminary screening in the rat shows that series 1 and 3 exhibit diuretic and saluretic activity similar to that of chlorothiazide with, however, Na+/K+ ratios more favorable than chlorothiazide and furosemide.The compounds of series 2 and 4 are practically inactive.All four series show initial antihypertensive activity lower than that of hydralazine.However, compounds 1a, 1c, and 4a show a higher activity at 8 and/ or 24 h after administration and thus may offer a unique combination of a "loop" diuresis with direct long-acting peripheral vasodilating effects.
