100500-85-4

Upstream product

• 129221-41-6 (5-Benzoyloxy-1-methyl-2-phenyl-1H-imidazol-4-yl)-triphenyl-phosphonium; iodide 
• 129221-27-8 C₃₄H₂₅N₂O₂P 
• 33243-93-5 C₁₂H₁₅NO₃ 
• 622-29-7 N-Benzylidenemethylamine 
• 1155-48-2 2-benzoylaminocinnamic acid 
• 556-61-6 methyl thioisocyanate 
• 129221-44-9 1-methyl-2-phenyl-5-oxo-4,5-dihydroimidazol-4-idenetriphenylphosphorane 
• 100-52-7 benzaldehyde 
• 74-89-5 methylamine 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 

Relevant academic research and scientific papers

Cycloaddition with stabilized imidates as potential azomethines ylides : A new route to 2-imidazoline and 4-yliden-s-imidazolinone

Imidates derived from α-amino esters, undergo cycloaddition reactions as stabilized ylides, with imines in good yields.

C-H?O interactions are favoured in the crystal structures of imidazolin-5-ones

The competing forces of a greater number of weak C-H?O interactions in the crystal structure of imidazolin-5-one analogues seem to tip the balance against the relatively stronger carbonyl-carbon (C=O δ-?Cδ+) electrostatic interaction previously observed and reported by us in the crystal structure of (4Z)-4-(4-methoxybenzylidene)-1,2-diphenyl-1,4-dihydro-5H-imidazolin-5-one [G. Bhattacharjya, G. Savitha, G. Ramanathan, Cryst. Eng. Commun. 6 (2004) 233].

Isothiocyanate-Mediated Condensation of N-Acyl-α-amino Acids with Aromatic Aldehydes: One-Pot Synthesis of 1,2-Disubstituted 4-Arylmethylene-2-imidazolin-5-ones

N-Acetyl/benzoyl-amino acids (1c/1b, d) when heated with isothiocyanates (2) in the presence of suitable aromatic aldehydes (3) with pyridine as a catalyst, afford 1, 2-disubstituted 4-arylmethylene-2-imidazolin-5-ones (6).However, N-benzyloxycarbonylaminoacetic acid (1a) gives the corresponding anilide (11a).Mechanisms of these reactions are discussed.