1155-48-2

Usage

Uses

Used in Pharmaceutical Applications:
2-(benzoylamino)-3-phenylprop-2-enoic acid is used as a pharmaceutical agent for its potential role in inhibiting the growth of cancer cells. It has been studied for its ability to target and affect the proliferation of various types of cancer, making it a promising candidate for further research and development in oncology.
Used in Drug Delivery Systems:
In the field of drug delivery, 2-(benzoylamino)-3-phenylprop-2-enoic acid is utilized as a component in the development of systems designed to improve the efficacy and targeted delivery of pharmaceuticals. Its chemical properties allow for potential integration into various drug delivery platforms, enhancing the compound's bioavailability and therapeutic impact.
Used in Research Applications:
2-(benzoylamino)-3-phenylprop-2-enoic acid serves as a valuable research tool in the scientific community. It is used in laboratories to study the mechanisms of action related to its potential anticancer properties and to explore new avenues for drug development, providing insights into the compound's interactions with biological systems.

Upstream product

• 32089-78-4 ethyl 2-(benzoylamino)-3-(phenyl)acrylate 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 15732-43-1 (E)-2-phenyl-4-benzylidene-5(4H)-oxazolone 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 18510-74-2 4-benzylidene-2,6-diphenyl-4H-[1,2,5]oxadiazin-3-one 
• 356791-01-0 N-(1-oxo-3-phenyl-1-(piperidin-1-yl)-prop-2-en-2-yl)benzamide 
• 18510-92-4 N-hydroxy-3,N-diphenyl-2-thiobenzoylamino-acrylamide 
• 16446-30-3 4-benzylidene-2-phenyl-4H-thiazol-5-one 
• 26348-47-0 (Z)-2-benzamidocinnamic acid 
• 100-52-7 benzaldehyde 
• 21462-02-2 methyl (Z)-2-benzoylamino-3-phenyl-2-propenoate 
• 27573-05-3 methyl ester of benzoylaminocinnamic acid 

Downstream Products

• 27573-05-3 methyl ester of benzoylaminocinnamic acid 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 
• 55-21-0 benzamide 
• 150-30-1 Phenylalanine 
• 6362-70-5 5-benzyl-4-phenyl-dihydro-furan-2,3-dione 
• 2566-22-5 DL-N-benzoylphenylalanine 
• 83556-31-4 Phac-DL-Phe-NH₂ 
• 23912-50-7 N-benzoyl-phenylalanine hydrazide 
• 17606-70-1 (4Z)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one 
• 153199-75-8 ethyl (1-benzoylamino-2-phenylethenyl)phenylphosphinate 
• 2566-22-5 N-benzoyl-L-phenylalanine 
• 37002-52-1 N-benzoyl-D-phenylalanine 
• 842-74-0 4-benzylidene-2-phenyloxazole-5(4H)-one 
• 144264-38-0 2-Benzoylamino-2,3-dichloro-3-phenyl-propionic acid 

Relevant academic research and scientific papers

Reaction of 2-Phenyl-4-arylidene-1,3-oxazolones with Different Nucleophiles for Synthesis of Some New Heterocycles

Refluxing of 1,3-oxazolone (1a) with malononitrile in dry benzene and in the presence of ammonium acetate afforded imidazolone derivative (2). However, carrying out the same reaction in absolute ethanol and in the presence of piperidine as a base gave the

Studies on the reactivity pattern of in situ generated tetraethylammonium superoxide with 2-oxazolin-5-ones

A variety of 2-oxazolin-5-ones have been allowed to react under the mild reaction conditions of potassium superoxide and tetraethylammonium bromide in dry dimethylformamide at room temperature. Different products are obtained depending on the substituents attached to the C-4 position.

Physical characteristics and polarographic reduction mechanism of some oxazolones

The redox potential (ΔE1/2), electron affinity (EA), ionization potential (IP), coulomb repulsion integral (J12), and electronic transition energy (ECT) of several oxazolone derivatives in DMF were computed.A linear correlation was shown to exist between ΔE1/2 and ECT.The polarographic reduction was investigated in ethanolic-Theil buffer solutions.At pH /= 7.2, two waves were obtained representing the uptake of 2- and 4-electron steps respectively.In alkaline media, a third wave appeared seemingly a result of the hydrolysis of oxazolones.The rate of hydrolysis was determined and the electrode mechanism was elucidated and confirmed via spectrophotometric and coulometric analysis. Key words: oxazolones, polarography, electrochemistry, electrode reaction, spectrophotometry, redox potential.

N-Acyl Dehydro-α-amino Acids from N-Formyl Dehydro-α-amino Acid Esters

On treatment with methyl potassioisocyanoacetate (2), aldehydes and ketones 1 give N-anionized N-formyl dehydro-α-amino acid methyl esters 3.Compounds 3 with R1 = CH3, R2 = H is obtained by base induced ring opening of methyl 2-oxazoline-4-carboxylate 5. - Acylation of 3, followed by deformation of the intermediates 6, yields N-acyl dehydro α-amino acid methyl esters 7 which can be hydrolyzed to the N-acyl dehydro α-amino-acids 8.